Journal of Advanced Surgical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-1518-081136

Short Communication - Journal of Advanced Surgical Research (2025) Volume 9, Issue 2

Ssi prevention: A comprehensive clinical toolkit

Clara Nguyen*

Department of Clinical Surgery, Sydney School of Medicine, University of Sydney, Sydney, Australia

*Corresponding Author:
Clara Nguyen
Department of Clinical Surgery
Sydney School of Medicine, University of Sydney, Sydney, Australia.
E-mail: clara.nguyen@uni-sydney.au

Received : 04-Apr-2025, Manuscript No. aaasr-203; Editor assigned : 08-Apr-2025, PreQC No. aaasr-203(PQ); Reviewed : 28-Apr-2025, QC No aaasr-203; Revised : 07-May-2025, Manuscript No. aaasr-203(R); Published : 16-May-2025 , DOI : 10.35841/2591-7765-9.2.203

Citation: Nguyen C. Ssi prevention: A comprehensive clinical toolkit. aaasr. 2025;09(02):203.

Visit for more related articles at Journal of Advanced Surgical Research

Introduction

This systematic review and meta-analysis thoroughly evaluated various surgical site infection (SSI) prevention practices. Drawing upon randomized controlled trials, it successfully identified highly effective interventions. These include specific skin antiseptic preparations and optimal antibiotic prophylaxis regimens, providing crucial evidence-based recommendations for clinical practice to significantly reduce SSI rates in surgical settings[1].

Another systematic review and meta-analysis explores how Enhanced Recovery After Surgery (ERAS) pathways impact surgical site infection (SSI) rates. The findings strongly suggest that implementing ERAS protocols, which encompass various integrated perioperative interventions, significantly contributes to reducing the incidence of SSIs across different surgical specialties[2].

Furthermore, a systematic review and meta-analysis meticulously examines various risk scores used to predict surgical site infections (SSIs). It carefully evaluates their predictive accuracy and clinical utility, aiming to identify the most robust tools for early identification of high-risk patients, enabling more targeted preventative measures[3].

This review specifically explores novel strategies for preventing surgical site infections (SSIs) in gastrointestinal surgery. It discusses emerging techniques and approaches beyond standard protocols, emphasizing tailored and innovative interventions to effectively reduce SSI incidence in complex abdominal procedures[4].

In a comprehensive systematic review and meta-analysis, key risk factors associated with surgical site infections (SSIs) following colorectal surgery were identified. It synthesizes evidence from a large number of studies, offering vital insights into patient-specific and procedural factors that contribute to SSI development in this high-risk patient group[5].

A systematic review and meta-analysis evaluates the profound impact of preoperative nutrition interventions on reducing surgical site infections (SSIs). It highlights the critical importance of optimizing nutritional status before surgery as a crucial component of SSI prevention, particularly in malnourished or high-risk patients needing enhanced care[6].

A quasi-experimental study investigates the effectiveness of an antimicrobial stewardship program in reducing surgical site infections (SSIs) within a tertiary hospital setting. It demonstrably shows how rationalizing antibiotic use can significantly contribute to lower SSI rates, supporting the integration of comprehensive stewardship initiatives into surgical practice[7].

This systematic review and meta-analysis assesses the efficacy of negative pressure wound therapy (NPWT) in preventing surgical site infections (SSIs). The findings indicate that NPWT can be a valuable adjunct in certain surgical contexts, particularly in high-risk wounds, effectively reducing SSI incidence and improving wound healing outcomes[8].

A systematic review and meta-analysis directly compares the efficacy of chlorhexidine-alcohol versus povidone-iodine for preventing surgical site infections (SSIs). It provides essential evidence-based insights into the optimal skin antiseptic choice for various surgical procedures, guiding clinical decisions for better patient outcomes and reduced infection risk[9].

Finally, a systematic review and meta-analysis investigates the optimal duration of prophylactic antibiotics for preventing surgical site infections (SSIs). It assesses whether prolonged antibiotic use offers additional benefit over shorter courses, aiming to guide practices that minimize resistance while maintaining optimal efficacy[10].

 

Conclusion

Research consistently highlights diverse strategies for preventing surgical site infections (SSIs). Systematic reviews and meta-analyses underscore the efficacy of specific skin antiseptic preparations and optimal antibiotic prophylaxis regimens, providing evidence-based recommendations for clinical practice. These studies evaluate interventions like chlorhexidine-alcohol versus povidone-iodine and investigate the ideal duration for prophylactic antibiotics to minimize resistance while maintaining effectiveness. Beyond chemical interventions, broader patient management plays a critical role. Enhanced Recovery After Surgery (ERAS) pathways, with their comprehensive perioperative interventions, are shown to significantly reduce SSI rates across various surgical specialties. Preoperative nutrition optimization is another crucial component, particularly for malnourished or high-risk patients, improving their resilience against infection. Identifying and mitigating risk are also central to prevention. Studies examine various risk scores to predict SSIs, evaluating their accuracy for early identification of high-risk patients, enabling targeted preventative measures. This includes specific analyses of risk factors for SSIs following colorectal surgery, a particularly high-risk area. Novel approaches and adjunctive therapies also show promise. Reviews explore emerging strategies for preventing SSIs in specialized fields like gastrointestinal surgery, focusing on tailored interventions. Negative pressure wound therapy (NPWT) is identified as a valuable adjunct for high-risk wounds, reducing SSI incidence and enhancing healing. Furthermore, antimicrobial stewardship programs effectively rationalize antibiotic use, significantly lowering SSI rates in hospital settings. Together, these findings offer a comprehensive toolkit for reducing SSIs and improving patient outcomes.

References

  1. Al-Habbal B, Al-Dossari N, Ghomraoui T. Surgical Site Infection Prevention Practices: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Hosp Infect. 2023;133:14-27.
  2. Indexed at, Google Scholar, Crossref

  3. Cao Y, Wu Y, Yang J. Impact of enhanced recovery after surgery (ERAS) pathways on surgical site infection rates: a systematic review and meta-analysis. Int J Surg. 2022;107:106883.
  4. Indexed at, Google Scholar, Crossref

  5. Ng I, Htoo M, Lau J. Predicting surgical site infection: A systematic review and meta-analysis of risk scores. J Infect Public Health. 2021;14(7):909-921.
  6. Indexed at, Google Scholar, Crossref

  7. Ishibashi T, Kawakami M, Kuramoto M. Novel strategies for prevention of surgical site infection in gastrointestinal surgery. Surg Today. 2020;50(1):1-10.
  8. Indexed at, Google Scholar, Crossref

  9. Tan M, Ong C, Chan M. Risk factors for surgical site infection after colorectal surgery: a systematic review and meta-analysis of 110 studies. Int J Surg. 2020;74:61-70.
  10. Indexed at, Google Scholar, Crossref

  11. Zhou Y, Zhang C, Liu D. The role of preoperative nutrition in reducing surgical site infections: a systematic review and meta-analysis. Nutrients. 2021;13(1):210.
  12. Indexed at, Google Scholar, Crossref

  13. Lim N, Lim M, Tang S. Implementation of an antimicrobial stewardship program to reduce surgical site infections in a tertiary hospital: a quasi-experimental study. Antimicrob Resist Infect Control. 2023;12(1):26.
  14. Indexed at, Google Scholar, Crossref

  15. Liu Z, Song H, Fu X. The role of negative pressure wound therapy in preventing surgical site infections: a systematic review and meta-analysis. Wound Repair Regen. 2022;30(5):544-556.
  16. Indexed at, Google Scholar, Crossref

  17. Dumville JC, Gray TA, Walter CJ. Efficacy of chlorhexidine-alcohol versus povidone-iodine for surgical site infection prevention: a systematic review and meta-analysis. Br J Surg. 2023;110(2):162-171.
  18. Indexed at, Google Scholar, Crossref

  19. Sun C, Cao W, Zheng Y. The role of prophylactic antibiotics duration in surgical site infection prevention: a systematic review and meta-analysis. Infect Drug Resist. 2024;17:217-230.
  20. Indexed at, Google Scholar, Crossref

Get the App