Rapid Communication - Materials Science and Nanotechnology (2023) Volume 7, Issue 3
Nanomaterials in biomedical engineering: Towards personalized medicine and therapeutics.
Department of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China
- *Corresponding Author:
- Jing Wang
Department of Pharmaceutical Biotechnology
The University of Hong Kong, Hong Kong
Received: 25-May-2023, Manuscript No. AAMSN-23-102823; Editor assigned: 27-May-2023, PreQC No. AAMSN-23-102823 (PQ); Reviewed: 03-Jun-2023, QC No. AAMSN-23-102823; Revised: 15-Jun-2023, Manuscript No. AAMSN-23-102823 (R); Published: 20-Jun-2023, DOI:10.35841/ aamsn-7.3.149
Citation: Wang J. Nanomaterials in biomedical engineering: Towards personalized medicine and therapeutics. Mater Sci Nanotechnol. 2023;7(3):149
In recent years, the field of biomedical engineering has witnessed remarkable advancements, particularly with the integration of nanotechnology. Nanomaterials, with their unique physical and chemical properties at the nanoscale, have revolutionized the landscape of personalized medicine and therapeutics. This article explores the applications of nanomaterials in biomedical engineering and highlights their potential in shaping the future of personalized medicine .
Nanomaterials have revolutionized drug delivery by enabling targeted and controlled release of therapeutic agents. By engineering nanocarriers with specific surface modifications, drug-loaded nanoparticles can be designed to selectively accumulate at the site of disease, minimizing off-target effects. These nanocarriers can also be functionalized to respond to specific stimuli, such as changes in pH or temperature, further enhancing their precision and efficacy. The ability to deliver therapeutics directly to diseased cells or tissues offers immense potential for personalized medicine, tailoring treatments based on individual patient characteristics .
Nanomaterials have paved the way for more sensitive and specific diagnostic techniques. Nanoparticles functionalized with targeting ligands and fluorescent dyes can be used as nanoprobes for imaging and detection of biomarkers associated with diseases. This allows for early disease diagnosis, facilitating timely intervention and treatment. Furthermore, multifunctional nanoprobes can combine diagnostic and therapeutic capabilities, enabling real-time monitoring of treatment response .
Nanomaterials play a crucial role in regenerative medicine, offering innovative approaches to tissue engineering and regeneration. Scaffold materials based on nanomaterials provide a biomimetic environment that supports cell adhesion, proliferation, and differentiation. By tailoring the composition, surface topography, and mechanical properties of nanomaterial-based scaffolds, researchers can mimic the native extracellular matrix and promote tissue regeneration. Moreover, nanomaterials can serve as vehicles for growth factors and biomolecules, enhancing their controlled release and bioactivity .
Nanomaterials have fuelled the development of highly sensitive biosensors and point-of-care devices for rapid and accurate disease diagnosis. Nanostructured materials, such as carbon nanotubes, graphene, and quantum dots, exhibit unique electrical, optical, and catalytic properties that enable ultrasensitive detection of biomarkers. These nanomaterial-based biosensors hold great potential for early detection of diseases, including cancer, infectious diseases, and metabolic disorders, enabling timely intervention and personalized treatment strategies. Theranostics, the integration of diagnostics and therapeutics, has been greatly advanced by nanomaterials. Theranostic nanoparticles combine imaging agents and therapeutic payloads into a single nanoplatform, enabling simultaneous disease diagnosis and treatment. Through the use of nanomaterials, theranostic nanoparticles can be precisely targeted to diseased tissues, allowing for image-guided therapy. This approach holds significant promise for personalized medicine, enabling physicians to monitor treatment response and adjust therapeutic strategies based on real-time feedback .
Nanomaterials have revolutionized the field of biomedical engineering, providing unprecedented opportunities for personalized medicine and therapeutics. From targeted drug delivery systems to regenerative medicine and diagnostic nanoprobes, nanomaterials have enabled precise and tailored approaches to disease diagnosis, treatment, and monitoring. The integration of nanotechnology in biomedical engineering holds immense potential for transforming healthcare, improving patient outcomes, and paving the way towards a future of personalized medicine. However, further research and development are necessary to address safety concerns and regulatory challenges associated with the clinical translation of nanomaterial-based technologies.
- Di Martino EF. Aktueller stand der tubenfunktionsdiagnostik. HNO. 2013;61(6):467-76.
- Rothammer M, Zollfrank C, Busch K, et al. Tailored disorder in photonics: learning from nature. Adv Opt Mater. 2021;9(19):2100787.
- Lee SG, Lee SN, Baek J, et al. Mechanical compression enhances ciliary beating through cytoskeleton remodeling in human nasal epithelial cells. Acta Biomater. 2021;128:346-56.
- Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021 ;71(3):209-49.
- Liu L, Oza S, Hogan D, et al. Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the Sustainable Development Goals. The Lancet. 2016 ;388(10063):3027-35.