Rapid Communication - Journal of Plant Biotechnology and Microbiology (2023) Volume 6, Issue 2
Molecular breeding innovations for unlocking plant genetic potentialAiden Clark*
Department of Plant and Animal Science, University of Guelph, Guelph, Canada
- *Corresponding Author:
- Aiden Clark
Department of Plant and Animal Science
University of Guelph, Guelph, Canada
Received: 29-Mar-2023, Manuscript No. AAPBM-23-95273; Editor assigned: 30-Mar-2023, PreQC No.AAPBM-23-95273(PQ); Reviewed: 14-Apr-2023, QC No.AAPBM-23-95273; Revised: 18-Apr-2023, Manuscript No. AAPBM-23-95273(R); Published: 27-Apr-2023, DOI: 10.35841/aapbm-6.2.138
Citation: Clark A. Molecular breeding innovations for unlocking plant genetic potential. J Plant Bio Technol. 2023;6(2):138
Plant breeding has been a fundamental practice for humans since the dawn of agriculture, aimed at improving the characteristics of crop plants for increased yield, disease resistance, and nutritional content. Over the years, traditional plant breeding techniques, such as cross-pollination and selection, have been used to develop improved plant varieties. However, with the advent of molecular breeding innovations, plant scientists are now able to unlock the full potential of plant genetics in a more precise and accelerated manner, leading to the development of improved crops with enhanced traits. Molecular breeding, also known as molecular-assisted breeding or marker-assisted breeding, is a modern plant breeding approach that utilizes molecular tools to identify, select, and manipulate specific genes or genomic regions associated with desirable traits in plants. This technique has revolutionized plant breeding by allowing breeders to work at the DNA level, which is the foundation of plant traits, and has significantly accelerated the breeding process .
One of the key molecular breeding innovations is the use of DNA markers, which are specific regions of DNA that can be easily identified and analyzed in a plant's genome. DNA markers can be associated with various plant traits, such as disease resistance, drought tolerance, and nutritional content, among others. By identifying and selecting plants with specific DNA markers associated with desirable traits, breeders can speed up the process of developing improved plant varieties. DNA markers are used in various molecular breeding techniques, such as marker-assisted selection (MAS) and genomic selection (GS). In MAS, DNA markers are used to select plants with specific desirable traits based on their DNA profile. For example, if a DNA marker is associated with resistance to a certain disease, breeders can screen plants for that DNA marker and select those that carry it, thereby increasing the chances of obtaining disease-resistant plants. In GS, DNA markers are used to predict the performance of plants for specific traits based on their genomic data, allowing breeders to select plants with the highest potential for desired traits, even at the seed or seedling stage .
Another significant molecular breeding innovation is gene editing techniques, such as CRISPR-Cas9, which allows breeders to precisely edit or modify specific genes in a plant's genome. Gene editing offers unprecedented precision and efficiency in plant breeding, as it enables breeders to make specific changes to the DNA sequence, resulting in precise modifications to plant traits. For example, breeders can use gene editing to create plants with improved nutritional content, such as higher levels of vitamins or minerals, or to develop plants with enhanced resistance to pests or diseases. Furthermore, molecular breeding has also enabled the transfer of desirable genes from wild relatives or other plant species into cultivated crops through a process known as transgenesis. Transgenic plants, also known as genetically modified organisms (GMOs), have been developed to express specific genes that confer traits such as herbicide tolerance, insect resistance, and improved nutritional content. These genetically modified plants have been widely used in agriculture, although they are subject to regulation and public scrutiny .
In addition to DNA markers, gene editing, and transgenesis, molecular breeding innovations also include techniques such as high-throughput sequencing, bioinformatics, and metabolomics, which allow breeders to analyze and understand the complex interactions between genes, environment, and plant traits. High-throughput sequencing enables breeders to quickly and cost-effectively sequence the entire genome of a plant, which provides a comprehensive understanding of its genetic makeup. Bioinformatics tools help in the analysis and interpretation of large genomic data sets, allowing breeders to identify key genes or pathways associated with specific traits. Metabolomics, on the other hand, involves the analysis of plant metabolites, which are the small molecules that play a crucial role in plant metabolism and influence various plant traits .
Molecular breeding innovations, including DNA markers, gene editing, transgenesis, high-throughput sequencing, bioinformatics, and metabolomics, have revolutionized plant breeding by unlocking the plant genetic potential in a more precise and accelerated manner. These innovations have resulted in the development of improved plant varieties with enhanced traits, such as increased yield, improved nutritional content, and better tolerance to environmental stresses. Molecular breeding has the potential to contribute to improved food security, sustainability, and nutrition, and has already shown promising results in addressing the challenges faced by modern agriculture .
- Cao HX, Wang W, Le HT, et al. The power of CRISPR-Cas9-induced genome editing to speed up plant breeding. Int J Genomics. 2016;2016.
- Friedrichs S, Takasu Y, Kearns P, et al. Meeting report of the OECD conference on “genome editing: applications in agriculture—implications for health, environment and regulation”. Transgenic Res. 2019; 28:419-463.
- Heller MA, Eisenberg RS. Can patents deter innovation? The anticommons in biomedical research. Sci. 1998;280(5364):698-701.
- Potrykus I. Lessons from the ‘Humanitarian Golden Rice’project: regulation prevents development of public good genetically engineered crop products. New Biotech. 2010;27(5):466-72.
- Egelie KJ, Graff GD, Strand SP, et al. The emerging patent landscape of CRISPR–Cas gene editing technology. Nature biotech. 2016;34(10):1025-31.