Opinion Article - Anesthesiology and Clinical Science Research (2025) Volume 9, Issue 2
Modern pain management: Integrated, opioid-sparing care
Priya Mehta*
Department of Pain Medicine, All India Institute of Medical Sciences, New Delhi, India
- *Corresponding Author:
- Priya Mehta
Department of Pain Medicine
All India Institute of Medical Sciences, New Delhi, India.
E-mail: priya.mehta@aiims.ac.in
Received : 02-Jun-2025, Manuscript No. aaacsr-212; Editor assigned : 04-Jun-2025, PreQC No. aaacsr-212(PQ); Reviewed : 24-Jun-2025, QC No aaacsr-212; Revised : 03-Jul-2025, Manuscript No. aaacsr-212(R); Published : 14-Jul-2025 , DOI : 10.35841/aaacsr-9.2.212
Citation: Mehta P. Modern pain management: Integrated, opioid-sparing care. aaacsr. 2025;09(02):212.
Introduction
Advances in both pharmacological and non-pharmacological approaches are reshaping pain management. This includes new drug developments, novel analgesics, and improved delivery systems, alongside a growing emphasis on interventional procedures, psychological therapies, and complementary medicine techniques. The focus now rests on integrated, patient-centered strategies designed to optimize pain relief, minimize adverse effects, and move towards a more holistic care model. [1] Understanding and managing neuropathic pain presents unique challenges, requiring a detailed exploration of various pharmacological agents like antidepressants, anticonvulsants, and topical agents. Beyond drugs, emerging therapies such as neurostimulation and psychological support are vital. This complexity necessitates individualized, multimodal treatment plans to effectively address the diverse etiologies and manifestations of neuropathic pain. [2] In surgical settings, the emphasis on non-opioid strategies for pain management has intensified, largely driven by concerns over the ongoing opioid crisis. Techniques like regional anesthesia, multimodal analgesia using Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), acetaminophen, gabapentinoids, and novel analgesic adjuncts are key. The goal is to ensure effective pain control while minimizing opioid exposure, promoting faster recovery, and improving patient outcomes. [3] The understanding and management of chronic widespread pain, encompassing conditions like fibromyalgia, continues to evolve. Recent advances highlight improved diagnostic criteria, deeper insights into neurobiological mechanisms, and diverse therapeutic interventions. A biopsychosocial approach is crucial, integrating pharmacological treatments with non-pharmacological strategies such as exercise, cognitive behavioral therapy, and other rehabilitative modalities, all tailored to individual patient needs. [4] Breakthrough cancer pain (BTCP) is a particularly challenging aspect of cancer care. Recent advancements in its assessment include validated screening tools and patient-reported outcome measures. Management strategies range from rapid-onset opioids to non-pharmacological approaches, underscoring the need for personalized treatment plans to effectively alleviate acute exacerbations of pain and enhance the quality of life for cancer patients. [5] In emergency departments, strategies for reducing opioid reliance in acute pain management are gaining prominence. Multimodal analgesia is essential, incorporating non-opioid medications such as NSAIDs, acetaminophen, and regional nerve blocks. The role of local anesthetics and alternative therapies is also being explored to provide effective pain relief while mitigating the significant risks of opioid misuse and addiction in acute care settings. [6] Psychological interventions play a significant role in chronic pain management. Systematic reviews synthesize findings on the efficacy of various psychotherapeutic approaches, including Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT), and mindfulness-based interventions. These therapies effectively address the significant impact of psychological factors on chronic pain, improving pain-related distress, functional ability, and overall quality of life for patients. [7] Integrative pain management is an expanding field for complex chronic pain conditions. It combines conventional medical treatments with complementary and alternative medicine (CAM) therapies such as acupuncture, chiropractic care, massage therapy, and mind-body practices. This combination offers a more comprehensive and patient-centered approach, emphasizing personalized care plans that address the multidimensional nature of chronic pain. [8] An updated review of multimodal analgesia (MMA) for postoperative pain management underscores its importance. This approach emphasizes combining analgesics with different mechanisms of action, including regional anesthesia, NSAIDs, acetaminophen, and gabapentinoids. The aim is to achieve superior pain relief, reduce opioid consumption, and mitigate associated side effects, with evidence-based strategies enhancing patient recovery and satisfaction across various surgical procedures. [9] Digital health interventions are exploring their application and effectiveness in chronic pain management. This scoping review examines technologies like mobile apps, telehealth platforms, and wearable devices that provide education, self-management tools, and remote support. Digital solutions offer great potential to improve access to care, enhance patient engagement, and deliver personalized pain management strategies, particularly beneficial for individuals living with chronic conditions. [10]
Conclusion
Current trends in pain management emphasize a shift towards integrated, patient-centered care, combining both pharmacological and non-pharmacological interventions. This holistic approach aims to optimize pain relief while minimizing adverse effects. Significant advancements include novel analgesics, improved drug delivery systems, and a greater reliance on interventional procedures, psychological therapies such as Cognitive Behavioral Therapy (CBT) and Acceptance and Commitment Therapy (ACT), and complementary medicine techniques. Specialized strategies are being developed for various pain conditions. For neuropathic pain, individualized multimodal treatment plans incorporate antidepressants, anticonvulsants, topical agents, neurostimulation, and psychological support. Managing chronic widespread pain, including fibromyalgia, increasingly adopts a biopsychosocial approach, integrating pharmacological treatments with exercise and rehabilitative modalities. Breakthrough cancer pain benefits from advanced assessment tools and personalized plans, often involving rapid-onset opioids alongside non-pharmacological methods. A critical focus is on reducing opioid reliance through opioid-sparing strategies and multimodal analgesia. In surgical settings and emergency departments, combinations of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), acetaminophen, gabapentinoids, regional anesthesia, and novel adjuncts provide effective pain control while mitigating the risks of opioid misuse and addiction. Furthermore, integrative pain management combines conventional medicine with complementary therapies like acupuncture and mind-body practices. Digital health interventions, including mobile apps and telehealth, are also improving access to personalized chronic pain management, reflecting a comprehensive and evolving landscape in pain care.
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