Archives of Digestive Disorders

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-1518081136

Opinion Article - Archives of Digestive Disorders (2025) Volume 7, Issue 2

Innovations in esophageal diagnostics and therapeutic

Anne Dubois*

Department of Digestive Health, Sorbonne University, France

*Corresponding Author:
Anne Dubois
Department of Digestive Health
Sorbonne University, France.
E-mail: adus@sorbonne.fr
Received : 05-Apr-2025, Manuscript No. AAADD-25-195; Editor assigned : 08-Apr-2025, PreQC No. AAADD-25-195(PQ); Reviewed : 28-Apr-2025, QC No AAADD-25-195; Revised : 07-May-2025, Manuscript No. AAADD-25-195(R); Published : 16-May-2025 , DOI : 10.35841/ aaadd-7.2.195

Citation: Dubois A. Innovations in esophageal diagnostics and therapeutic. Arch Dig Disord. 2025;07(02):195.

Visit for more related articles at Archives of Digestive Disorders

Introduction

This study offers robust long-term data on peroral endoscopic myotomy (POEM) for achalasia, demonstrating its effectiveness in maintaining symptom control and improving quality of life over several years, with favorable safety outcomes. It highlights POEM as a durable treatment option for patients[1].

This comprehensive update on GERD provides a detailed overview of current diagnostic approaches, including advanced pH monitoring and endoscopy, and outlines evidence-based management strategies, from lifestyle modifications and pharmacological therapies to surgical interventions, emphasizing patient-specific care pathways[2].

This article examines Barrett's esophagus, focusing on its diagnosis, risk stratification for progression to esophageal adenocarcinoma, and current management strategies including endoscopic therapy for dysplasia and early cancer, alongside surveillance protocols. It stresses the importance of individualized patient care based on risk factors[3].

This publication offers an updated perspective on Eosinophilic Esophagitis (EoE), detailing diagnostic criteria, established and emerging therapeutic approaches including dietary management, proton pump inhibitors, and topical steroids, alongside biologics, highlighting the evolving landscape for both adult and pediatric patients[4].

This comprehensive guideline outlines the multidisciplinary management of esophageal and esophagogastric junction cancers, covering diagnostic workup, staging, and treatment algorithms for localized and advanced disease, emphasizing tailored approaches incorporating surgery, chemotherapy, and radiation therapy[5].

This paper provides an essential update on the Chicago Classification version 4.0 for interpreting high-resolution esophageal manometry, offering refined diagnostic criteria for various esophageal motility disorders, including achalasia variants and ineffective esophageal motility, improving clinical precision[6].

This review addresses caustic esophageal injury in adults, outlining critical management strategies from immediate resuscitation and endoscopic evaluation to long-term surveillance for stricture formation and potential malignancy, emphasizing the multidisciplinary approach required for optimal outcomes[7].

This article delves into functional esophageal disorders, reviewing the updated Rome IV criteria for diagnosis, and discussing the physiological basis and evolving therapeutic landscape for conditions like functional heartburn and esophageal hypersensitivity, emphasizing neuromodulation and behavioral therapies[8].

This report summarizes key updates from the Baveno VII consensus on portal hypertension, providing crucial guidance on screening, prevention, and management of esophageal varices in patients with cirrhosis, including pharmacological therapies and endoscopic interventions, to reduce bleeding risk[9].

This article reviews contemporary endoscopic treatment strategies for benign esophageal strictures, including dilation techniques, stricture incision, and the use of intralesional steroid injections, providing insights into optimizing patient outcomes and minimizing recurrence[10].

 

Conclusion

This collection of research highlights critical advancements across a broad spectrum of esophageal disorders, encompassing both diagnostic and therapeutic innovations. It details the long-term efficacy of Peroral Endoscopic Myotomy (POEM) for achalasia, emphasizing its role in sustained symptom control and improved quality of life. The updated Chicago Classification version 4.0 for high-resolution manometry is presented as a key tool for refining the diagnosis of various motility disorders. Comprehensive updates are provided on Gastroesophageal Reflux Disease (GERD) and Eosinophilic Esophagitis (EoE), outlining diagnostic approaches and evolving management strategies, from lifestyle changes and pharmacology to advanced biologics. The data also delves into the complexities of Barrett's Esophagus, focusing on risk stratification and endoscopic therapies to prevent progression to adenocarcinoma. Multidisciplinary guidelines for esophageal and esophagogastric junction cancers are reviewed, stressing tailored treatment plans involving surgery, chemotherapy, and radiation. Moreover, the collection covers functional esophageal disorders, reviewing the Rome IV criteria and exploring neuromodulation and behavioral therapies. It addresses acute conditions like caustic esophageal injury, detailing urgent and long-term management. The Baveno VII consensus provides crucial guidance on managing esophageal varices in portal hypertension, while contemporary endoscopic techniques for benign esophageal strictures, including dilation and steroid injections, are also discussed. This body of work collectively underscores a patient-centric, evolving landscape in esophageal care, driven by continuous advancements in diagnostics and therapeutic interventions.

References

    1. Franciscus AMP, Marije LvdH, Patricia JvdS. Long-term Clinical Outcome of Peroral Endoscopic Myotomy for Achalasia: A Dutch Multicenter Cohort Study. Am J Gastroenterol. 2023;118(1):80-87.

Indexed at, Google Scholar, Crossref

    1. Philip OK, Kyle BD, Felice HS. Update on the Diagnosis and Management of Gastroesophageal Reflux Disease. JAMA. 2022;327(2):160-170.

Indexed at, Google Scholar, Crossref

    1. Matthias VK, David LH, Nicholas JS. Diagnosis and management of Barrett's esophagus. N Engl J Med. 2023;388(18):1709-1721.

Indexed at, Google Scholar, Crossref

    1. Evan SD, David AK, Glenn TF. Update on the diagnosis and management of eosinophilic esophagitis. Gastroenterology. 2022;162(5):1406-1414.

Indexed at, Google Scholar, Crossref

    1. Jaffer AA, Thomas AD, Khaldoun A. Esophageal and esophagogastric junction cancers, version 2.2020. J Natl Compr Canc Netw. 2020;18(7):856-881.

Indexed at, Google Scholar, Crossref

    1. Sabine R, Peter JK, John EP. High-resolution manometry: an update on Chicago classification version 4.0. Neurogastroenterol Motil. 2021;33(5):e14144.

Indexed at, Google Scholar, Crossref

    1. Micha? C, Kinga MW, Jan A. Caustic esophageal injury in adults: A review of current management strategies. World J Gastroenterol. 2020;26(17):1993-2003.

Indexed at, Google Scholar, Crossref

    1. Qasim A, Ronnie F, Daniel S. Functional esophageal disorders: Rome IV criteria and beyond. Curr Opin Gastroenterol. 2022;38(4):329-335.

Indexed at, Google Scholar, Crossref

    1. Guadalupe G, Juan GA, Christophe B. The new Baveno VII consensus report: highlights on portal hypertension. J Hepatol. 2021;75(5):1018-1020.

Indexed at, Google Scholar, Crossref

    1. Nienke HvdH, Stefan EM, Wendy LC. Endoscopic treatment of benign esophageal strictures: an update. Curr Opin Gastroenterol. 2020;36(5):416-422.

Indexed at, Google Scholar, Crossref

Get the App