Journal of Veterinary Medicine and Allied Science

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Opinion Article - Journal of Veterinary Medicine and Allied Science (2022) Volume 6, Issue 6

Genetic variations alter gene activity in animals

Stephane Metayer*

Department of Veterinary Clinical Science, University of Zurich, Zurich, Switzerland

*Corresponding Author:
Stephane Metayer
Department of Veterinary Clinical Science
University of Zurich
Zurich, Switzerland

Received: 02-Nov-2022, Manuscript No. AAVMAS-22-81681; Editor assigned: 05-Nov-2022, PreQC No. AAVMAS-22-81681(PQ); Reviewed: 19-Nov-2022, QC No. AAVMAS-22-81681;Revised: 23-Nov-2022, Manuscript No. AAVMAS-22-81681(R); Published: 30-Nov-2022, DOI:10.35841/2591-7978-6.6.130

Citation: Metayer S. Genetic variations alter gene activity in animals. J Vet Med Allied Sci. 2022;6(6):130

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Genetic alterations that alter gene activity or protein function can create many phenotypes into an organism. If a characteristic is advantageous and aids in the individual's survival and reproduction, it is more likely to be handed down to the next generation. The genetic make-up of organisms within a population changes, and this is what is meant by genetic variation. Genes are inherited sections of DNA that hold protein-production instructions. Alleles, which are different variations of a gene, are what determine the unique features that can be carried from one generation to the next. Breeding animals is the deliberate mating of animals with desirable genetic qualities in order to preserve or improve those traits in subsequent generations. This entails estimating the genetic worth of individuals in cattle for features like growth rate and yield of goods like eggs, milk, or meat.

Purebred breeding is the practise of mating only animals of the same breed in order to preserve that breed. Purebred breeding, as opposed to the technique of mating animals of various breeds, strives to establish and retain stable qualities that animals will pass on to the following generation [1]. One may create a lineage or breed that was superior in some ways to the original base stock by breeding the best to the best, using a certain amount of inbreeding, significant culling, and selection for superior attributes. Animals from different breeds must be mated in order to crossbreed [2]. Typically, breeds are chosen based on complementing features that will raise the economic value of the offspring. The breeding of pigs from the Yorkshire and Duroc breeds is one example. These breeds compliment one another since Durocs are extremely muscular and have other desirable characteristics while Yorkshires have adequate rates of muscle gain and have large litter sizes. Beef cattle like Angus and Charolais are another illustration. Because Charolais are particularly huge and Angus provide high-grade beef, crossbreeding results in an animal of acceptable quality and size.

Domestic animals usually suffer from inbreeding. Reduced fertility, slower growth rates, increased vulnerability to disease, and higher mortality rates are all associated with increased inbreeding [3]. As a result, breeders make an effort to keep related animals from mating. However, when long-term selection for the same qualities is carried out within a small population, some inbreeding tends to occur because parents of future generations are typically the best prospects from the last generation. Although inbreeding rates can be decreased, it will be necessary to introduce more varied genes if inbreeding depression becomes apparent. The most typical technique involves crossbreeding in some way. Up till now, quantitative techniques have contributed to genetic advancement in domestic animals [4]. Knowing the genes responsible for the various domestic animal features that are important economically would be highly valuable. This ought to improve selection accuracy. Finding chromosomal regions with high likelihood of coding genes in livestock is being done using data from sequencing human and other species' genes. A different strategy is to scan a section of a chromosome and search for correlations with economic characteristics.

Immunogenetics is a relatively new field of study that focuses on the relationship between an organism's genetic makeup and its immune system as well as practical applications of that knowledge. In order for producers to be profitable, they must in particular control infections in their cattle [5]. Although most infections can be prevented with vaccines, good hygiene, and other treatment measures, none of these are fully effective, and vaccines are expensive. Experiments and field data, however, provide indications of some genetic control over the immune system in both humans and animals. The three basic mechanisms that cause genetic variety are sexual reproduction, gene flow, and DNA mutation. Because environments are unstable, populations with genetic diversity will be better able to adapt to shifting conditions than populations without genetic diversity.

Natural selection and biological evolution are processes that depend on genetic variety. Natural selection does not take place, but genetic variants that develop in a population do. Genetic variations in a population interact with the environment to produce natural selection. Which genetic variations are more advantageous or better adapted for survival depends on the environment. More advantageous features are transmitted to the population as a whole when creatures with these environmentally chosen genes live and reproduce.


  1. Portugal GS, Gould TJ. Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behav Brain Res. 2008;193(1):1-6.
  2. Indexed at, Google scholar, Cross Ref

  3. Eicher JD, Gruen JR. Imaging-genetics in dyslexia: connecting risk genetic variants to brain neuroimaging and ultimately to reading impairments. Mol Genet Metab. 2013;110(3):201-12.
  4. Indexed at, Google scholar, Cross Ref

  5. Hoffmann AA, Daborn PJ. Towards genetic markers in animal populations as biomonitors for human?induced environmental change. Ecol Lett. 2007;10(1):63-76.
  6. Indexed at, Google scholar, Cross Ref

  7. Kas MJ, Gelegen C, Schalkwyk LC, et al. Interspecies comparisons of functional genetic variations and their implications in neuropsychiatry. Am J Med Genet B Neuropsychiatr Genet. 2009;150(3):309-17.
  8. Indexed at, Google scholar, Cross Ref

  9. Craig IW. The importance of stress and genetic variation in human aggression. Bioessays. 2007;29(3):227-36.
  10. Indexed at, Google scholar, Cross Ref

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