Rapid Communication - Anesthesiology and Clinical Science Research (2025) Volume 9, Issue 2
Evolving neuraxial anesthesia: Safety, scope, future
Anjali Deshpande*
Department of Anesthesiology, Tata Memorial Hospital, Mumbai, India
- *Corresponding Author:
- Anjali Deshpande
Department of Anesthesiology
Tata Memorial Hospital, Mumbai, India.
E-mail: anjali.deshpande@tmh.org.in
Received : 02-Jun-2025, Manuscript No. aaacsr-219; Editor assigned : 04-Jun-2025, PreQC No. aaacsr-219(PQ); Reviewed : 24-Jun-2025, QC No aaacsr-219; Revised : 03-Jul-2025, Manuscript No. aaacsr-219(R); Published : 14-Jul-2025 , DOI : 10.35841/aaacsr-9.2.219
Citation: Deshpande A. Evolving neuraxial anesthesia: Safety, scope, future. aaacsr. 2025;09(02):219.
Introduction
Neuraxial anesthesia and blocks represent fundamental techniques in contemporary medical practice, offering substantial benefits across a diverse range of clinical scenarios. Understanding their application, evolution, and management is crucial for optimizing patient care. This comprehensive overview draws on recent research to highlight key developments and challenges in the field. Managing persistent neurological injuries after neuraxial blocks demands a proactive strategy, emphasizing the critical role of early recognition and a collaborative, multidisciplinary approach. This ensures optimal patient outcomes by addressing both immediate interventions and long-term rehabilitative needs [1].
The implementation of ultrasound guidance for neuraxial blocks in pregnant women has been shown to significantly improve success rates and reduce the number of needle passes. This method is particularly effective in optimizing procedures for patients who present with challenging anatomical variations [2].
The unique challenges posed by the COVID-19 pandemic necessitated a thorough review of neuraxial block application and management. Clinical recommendations, grounded in current evidence, help practitioners navigate risks like viral spread and coagulopathy in this specific patient population [3].
For labor pain relief, a meta-analysis indicates that combined spinal-epidural (CSE) anesthesia offers a faster onset of analgesia. Importantly, it maintains safety profiles comparable to epidural anesthesia alone, positioning it as a highly effective option for managing labor pain [4].
When considering orthopedic surgeries, neuraxial blocks consistently demonstrate better patient outcomes compared to general anesthesia. These benefits include reduced blood loss and fewer postoperative complications, making neuraxial techniques a compelling choice for such procedures [5].
In the context of hip fracture surgery for older patients, neuraxial anesthesia emerges as a safer alternative to general anesthesia. This technique has been shown to significantly decrease perioperative morbidity and mortality within this vulnerable demographic [6].
For patients suffering from chronic low back pain, interventional neuraxial procedures offer a valuable therapeutic avenue. The effectiveness of these diverse techniques hinges on meticulous patient selection and precise procedural accuracy to achieve significant pain relief and functional improvement [7].
The impact of neuraxial anesthesia on outcomes in cardiac surgery is noteworthy, with findings suggesting that these techniques can lead to reduced postoperative pain and a lower incidence of pulmonary complications. This contributes to potentially improved overall recovery for complex cardiac patients [8].
Significant strides have been made in the development of opioid-free neuraxial anesthesia. This innovative approach explores various techniques and pharmacological adjuncts to provide effective pain management, critically minimizing the adverse effects typically associated with opioid use [9].
A comparison of regional anesthesia, including neuraxial blocks, with general anesthesia for total knee arthroplasty highlights clear advantages for regional techniques. These include reduced postoperative pain, decreased opioid consumption, and shorter hospital stays, firmly supporting their widespread adoption [10].
Conclusion
Neuraxial blocks represent a cornerstone of modern anesthesia, offering a versatile approach with continuously evolving applications and management strategies. The field is keenly focused on enhancing patient safety and outcomes. Current research highlights the crucial importance of early recognition and a multidisciplinary approach in managing persistent neurological injuries that can occur after a neuraxial block. This includes a comprehensive strategy addressing both immediate interventions and long-term rehabilitative support to optimize recovery. Technological advancements, such as the use of ultrasound guidance for neuraxial blocks in pregnant women, have demonstrably improved procedural success rates and significantly reduced the number of needle passes. This technique proves particularly beneficial for patients presenting with complex anatomical challenges, making the procedure safer and more efficient. Beyond obstetrics, the utility of neuraxial techniques spans across a wide range of surgical contexts. For orthopedic procedures, including total knee arthroplasty, neuraxial blocks are consistently shown to lead to superior patient outcomes. These benefits encompass reduced blood loss, fewer postoperative complications, decreased reliance on opioids for pain management, and notably shorter hospital stays when compared to general anesthesia. In the specialized realm of cardiac surgery, integrating neuraxial anesthesia has been linked to several positive effects. Patients experience reduced postoperative pain and a lower incidence of pulmonary complications, ultimately contributing to an improved overall recovery trajectory for these often-complex cases. Moreover, neuraxial anesthesia offers a safer alternative for vulnerable populations, such as older patients undergoing hip fracture surgery. Here, these techniques can significantly diminish perioperative morbidity and mortality, underscoring their critical role in optimizing care for the elderly. The unprecedented challenges of the COVID-19 pandemic necessitated specific clinical recommendations for neuraxial blockade, focusing on mitigating risks related to potential viral spread and coagulopathy in affected patients. In pain management, combined spinal-epidural (CSE) anesthesia has proven to offer a faster onset of analgesia for labor pain relief with safety profiles comparable to epidural anesthesia alone, providing an excellent option for parturients. Additionally, interventional neuraxial procedures are increasingly recognized for their effectiveness in treating chronic low back pain, with successful outcomes relying heavily on careful patient selection and precise procedural execution. Looking forward, significant progress is underway in developing opioid-free neuraxial anesthesia techniques. This involves exploring various pharmacological adjuncts and innovative approaches to achieve potent pain control while effectively minimizing the undesirable side effects commonly associated with opioid use, marking a substantial step forward in patient-centered care.
References
- Kianoush G, Deborah ES, Mary C. Current management of persistent neurologic injury after neuraxial block. Curr Opin Anaesthesiol. 2023;36(3):308-316.
- Gang H, Jian L, Jian W. Ultrasound-guided neuraxial block in pregnant women: A systematic review and meta-analysis. Int J Obstet Anesth. 2022;50:103551.
- Yasser A, Maged M, Abdulrahman A. Neuraxial blockade and COVID-19: a systematic review of current evidence and clinical recommendations. Egypt J Anaesth. 2021;37(1):500-508.
- Xiao C, Sen L, Yu Z. Analgesic effect and adverse reactions of combined spinal-epidural anesthesia versus epidural anesthesia for labor analgesia: A meta-analysis. Medicine (Baltimore). 2020;99(3):e18820.
- Xiang W, Xiaofei X, Qi W. Neuraxial Block versus General Anesthesia in Orthopedic Surgery: A Systematic Review and Meta-Analysis. Pain Res Manag. 2021;2021:6654060.
- Thiago JA, Leonardo SC, Viviane IA. Neuraxial anesthesia for hip fracture surgery in the elderly: A narrative review. J Clin Anesth. 2021;70:110178.
- Pavan G, Joseph VPJ, Robert TJ. Interventional Neuraxial Pain Procedures for Chronic Low Back Pain: A Narrative Review. Pain Ther. 2022;11(4):1199-1221.
- Ying G, Yong C, Mao T. Impact of Neuraxial Anesthesia on Outcomes in Cardiac Surgery: A Systematic Review and Meta-Analysis. J Cardiothorac Vasc Anesth. 2023;37(4):645-654.
- Kariem E, Ki JC, Stephen K. Recent Advances in Neuraxial Opioid-Free Anesthesia. Anesthesiology. 2023;138(6):830-843.
- Rohan K, Pradeep D, Mandar V. Regional versus general anesthesia for total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials. BMC Anesthesiol. 2023;23(1):21.
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