Journal of Parasitic Diseases: Diagnosis and Therapy

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Perspective - Journal of Parasitic Diseases: Diagnosis and Therapy (2025) Volume 10, Issue 3

Advancements and Challenges in the Diagnosis of Parasitic Infections: A Short Communication

James Mwangi*

Kenya Medical Research Institute (KEMRI), Kenya

Corresponding Author:
James Mwangi
Kenya Medical Research Institute (KEMRI),
Kenya Medical Research Institute (KEMRI),
kENYA
E-mail: maria.silva@usp.br

Received: 02-Aug-2025, Manuscript No. AAPDDT-25-166523; Editor assigned: 03-Aug-2025, AAPDDT-25-166523 (PQ); Reviewed: 17-Aug-2025, QC No. AAPDDT-25-166523; Revised: 22-Aug-2025, Manuscript No. AAPDDT-25-166523 (R); Published: 30-Aug-2025, DOI:10.35841/2591-7846.10.3.229

Citation: Mwangi J. Advancements and Challenges in the Diagnosis of Parasitic Infections: A Short Communication, J Parasit Dis Diagn Ther. 2025; 10(3):229

Introduction

Parasitic infections, caused by protozoa and helminths, affect millions worldwide and are often underdiagnosed due to limited access to diagnostic tools. Accurate identification is essential for appropriate treatment, disease control, and epidemiological surveillance. This communication provides an overview of current diagnostic modalities with emphasis on evolving technologies. Parasitic infections continue to pose a major global health burden, particularly in tropical and subtropical regions. Early and accurate diagnosis plays a pivotal role in effective management and control of these diseases. This short communication highlights key diagnostic approaches—ranging from traditional microscopy to modern molecular and immunological methods—while outlining their limitations, advantages, and future potential [1, 2, 3, 4].

Current Diagnostic Approaches: Microscopy: Conventional microscopy remains a cornerstone, especially in resource-limited settings. Though inexpensive and accessible, its accuracy is dependent on the skill of the technician and parasite load. Serological Tests: Techniques like ELISA and IFA detect parasite-specific antibodies or antigens. They are useful for chronic infections but may show cross-reactivity and cannot always differentiate active from past infections [5, 6].

Molecular Techniques: PCR and loop-mediated isothermal amplification (LAMP) have revolutionized parasite detection with high sensitivity and specificity. However, cost and technical requirements limit their field applicability. Rapid Diagnostic Tests (RDTs): RDTs offer point-of[1]care utility, especially in malaria detection. While fast and user-friendly, they sometimes lack sensitivity for low parasitemia. Imaging and Biopsy: Advanced imaging (e.g., CT, MRI) can aid diagnosis in cases like neurocysticercosis but are limited by availability and cost. Challenges and Future Directions: Access to diagnostics in low-income regions remains a significant barrier [7, 8, 9, 10].

Conclusion

Standardization of molecular and serological assays is essential for reproducibility. Integration of AI and biosensors may enhance real-time diagnostics and automation in the future. Multiplex diagnostics are emerging to simultaneously detect co-infections. Conclusion While traditional methods still serve as the backbone of parasitic diagnosis, modern molecular and immunological tools are shaping the future. Bridging the gap between laboratory advancement and field applicability is crucial to ensuring equitable healthcare outcomes globally.

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