Journal of Gastroenterology and Digestive Diseases

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Perspective - Journal of Gastroenterology and Digestive Diseases (2022) Volume 7, Issue 1

Accessing the mortality of patients with operative repair of ruptured abdominal aortic aneurysm.

Peter M. Haddison*

Department of Medical Biochemistry, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden

*Corresponding Author:
Peter M. Haddison
Institute of Biomedicine,
University of Gothenburg,
Gothenburg, Sweden
E-mail: peter.haddison@

Received: 21-Dec-2021, Manuscript No. JGDD-21-105; Editor assigned: 23-Dec-2021, PreQC No. JGDD-21-105 (PQ); Reviewed: 13-Jan-2022, QC No. JGDD-21-105; Revised: 21-Jan-2022, Manuscript No. JGDD-21-105 (R); Published: 28-Jan-2022, DOI: 10.35841/jgdd-7.1.105

Citation: Peter MH. Accessing the mortality of patients with operative repair of ruptured abdominal aortic aneurysm. J Gastroenterology Dig Dis. 2022; 7(1):105

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Abdominal aortic aneurysm causes

In affluent countries, abdominal aortic aneurysms account for 1.3 percent of all deaths in males aged 65 to 85. These aneurysms are usually asymptomatic until they rupture, which can be fatal. Large or symptomatic aneurysms should be repaired with open surgery or endovascular repair, whereas minor abdominal aortic aneurysms should not be repaired. The degeneration of the elastic media of the atheromatous aorta is associated to abdominal aortic aneurysm. The development of this illness is aided by an inflammatory cell infiltrate, neovascularization, and the synthesis and activation of different proteases and cytokines, albeit the underlying mechanisms are unknown. To offer family practitioners with a working knowledge of abdominal aortic aneurysm, we intend to present an updated review of the pathogenesis, existing and new diagnostic techniques, assessment, and therapy of this illness in this paper. [1].

Aortic aneurysm management

The majority of patients opt for stent-graft repair of abdominal and thoracic aneurysms in the endovascular era, which has revolutionised the management of aortic aneurysm disease. Primary care, emergency medicine, medicine specialists, and vascular surgeons all need to know about this vascular issue. Physicians can screen relevant patient populations for aneurysmal degeneration, sac rupture, and medical management if they are aware of the patient risk factors for aneurysmal degeneration, sac rupture, and medical therapy. This reduces aneurysm-related mortality owing to rupture. With the advancement of endovascular procedures, more patients are now eligible for this less invasive procedure, which has lower mortality and morbidity than open surgery with aorta replacement. The genesis, natural history, evaluation, and therapy of aortic aneurysm disease are all covered in this review [2].

Prior aortic repair complications, whether endovascular or open surgery, are equally important to understand not only for vascular surgeons performing these procedures, but also for primary care, emergency department, and medicine specialists evaluating these patients in an office or hospital setting [2].

Chronic dilation of the aorta

A persistent dilatation of the aorta with a natural history of expansion and rupture is known as an abdominal aortic aneurysm. It is thought to have a complicated and complex aetiology. Asymptomatic, symptomatic, or ruptured clinical manifestation is possible. The most common repair procedure is elective surgery via an open transperitoneal or retroperitoneal route. However, as an alternative to surgical surgery, putting an endoluminal stent graft within the aneurysm is currently being investigated. The nursing treatment of a patient with an abdominal aortic aneurysm necessitates both intense care and a solid understanding of chronic illness management. The pathophysiology, natural history, clinical presentation, surgical treatments, and postoperative complications are all covered in this article [3].

This article examines the molecular mechanisms underlying the regeneration of various mucosal epithelia, with a focus on the complicated situation that exists in the stomach mucosa and glands. For example, the histology, regeneration rates, and regeneration profiles of the two major types of stomach units, the fundic and antral types, differ significantly. Currently, a rough picture of the molecular mechanisms underpinning the phenomenon is emerging, which includes the characterisation of many somatic stem cell types and stem cell signalling pathways. Furthermore, dysregulated regeneration is now recognised as a contributing factor in a variety of metaplasias (reversible epithelia remodelling) and cancers, with chronic inflammation playing a significant role [3].

Epidemiology and contemporary management

The most frequent definition of an abdominal aortic aneurysm (AAA) is a maximal diameter of the abdominal aorta greater than 3 cm in either the anterior-posterior or transverse planes, or a focal dilation greater than 1.5 times the diameter of the normal surrounding arterial segment. Age > 60, cigarette usage, male gender, Caucasian race, and a family history of AAA are all risk factors for the development of AAA. Persistent cigarette use, female gender, and chronic pulmonary disease appear to be linked to aneurysm growth and rupture risk. The majority of AAAs are asymptomatic and discovered by chance through imaging tests such as abdominal ultrasonography and computed tomographic angiography. Abdominal or back pain, thromboembolization, atheroembolization, aortic rupture, or the formation of an arteriovenous or aortoenteric fistula is all symptoms of AAA [4].


For asymptomatic patients with AAAs less than 5 cm in diameter, medical therapy is suggested, with an emphasis on modifiable risk factors like as smoking cessation and blood pressure control. The onset of symptoms, rupture, fast aneurysm growth (> 5 mm/6 months), or the existence of a fusiform aneurysm with a maximal diameter of 5.5 cm or higher are the primary indications for intervention in individuals with AAA.


  1. Sakalihasan N, Limet R, Defawe OD. Abdominal aortic aneurysm. Lancet. 2005; 365(9470):1577-89.
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  3. Calero A, Illig KA. Overview of aortic aneurysm management in the endovascular era. Semin Vasc Surg. 2016; 29(1-2):3-17.
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  7. Ullery BW, Hallett RL, Fleischmann D. Epidemiology and contemporary management of abdominal aortic aneurysms. Abdom Radiol (NY). 2018; 43(5):1032-1043.
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