Journal of Dermatology Research and Skin Care

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Rapid Communication - Journal of Dermatology Research and Skin Care (2023) Volume 7, Issue 4

A brief note on types of skin biopsies.

John Welshman*

Department of Dermatology and Venereology, Martin Luther University Halle?Wittenberg, Ernst?Kromayer, Germany

*Corresponding Author:
John Welshman
Department of Dermatology and Venereology
Martin Luther University Halle?Wittenberg
Ernst?Kromayer, Germany

Received:28-Jul-2023,Manuscript No. AADRSC-23-109821; Editor assigned: 01-Aug-2023, PreQC No. AADRSC-23-109821(PQ); Reviewed:15-Aug-2023, QC No. AADRSC-23-109821; Revised:21-Aug-2023, Manuscript No. AADRSC-23-109821(R); Published:28-Aug-2023, DOI: 10.35841/aadrsc- 7.4.160

Citation: Welshman J. A brief note on types of skin biopsies. Dermatol Res Skin Care. 2023; 7(4):160

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Skin biopsies are essential diagnostic procedures used by dermatologists and healthcare professionals to accurately diagnose various skin conditions and diseases. These procedures involve the removal of a small sample of skin tissue for microscopic examination. Different types of skin biopsies exist, each suited for specific diagnostic purposes. Choosing the appropriate biopsy approach is crucial in ensuring accurate diagnosis and guiding appropriate treatment plans. In this article, we will explore the various types of skin biopsies available, their indications, techniques, and advantages, helping clinicians make informed decisions in selecting the most suitable approach for their patients.

Excisional biopsy

Excisional biopsy involves the complete removal of the entire skin lesion or a part of it. This type of biopsy is commonly used when there is suspicion of malignancy, such as melanoma or squamous cell carcinoma. The excisional biopsy provides a comprehensive sample for accurate diagnosis and staging, allowing for proper treatment planning. After excision, the wound is closed using sutures or other wound closure methods.

  • Indications: Suspicion of malignancy, large or deep lesions.
  • Technique: Complete removal of the lesion with a margin of healthy tissue.
  •  Advantages: Provides a full-thickness sample, suitable for accurate diagnosis and staging[1].

Incisional biopsy

Unlike excisional biopsy, incisional biopsy involves the removal of only a portion of the lesion. This type of biopsy is useful when dealing with large lesions where complete removal would be impractical. Incisional biopsies are often performed to assess the nature of the lesion before deciding on further treatment.

  • Indications: Large lesions, lesions with uncertain diagnosis.
  • Technique: Removal of a representative portion of the lesion.
  • Advantages: Allows for diagnosis without completely excising the lesion.

Punch biopsy

Punch biopsy is a commonly performed procedure that involves the use of a circular cutting tool to remove a small cylindrical sample of skin tissue. This technique is suitable for diagnosing a variety of skin conditions, including inflammatory disorders and small lesions.

  • Indications: Superficial lesions, inflammatory disorders.
  • Technique: Removal of a small cylindrical core of tissue.
  • Advantages: Minimally invasive, suitable for various skin conditions[2].

Shave biopsy

Shave biopsy is employed to remove the top layers of the skin, including the epidermis and a portion of the dermis. It is useful for diagnosing superficial lesions, such as moles, warts, and certain non-melanoma skin cancers. Shave biopsies are less invasive and typically result in minimal scarring.

  • Indications: Superficial lesions, moles, warts.
  • Technique: Shaving off the top layers of the lesion.
  • Advantages: Minimally invasive, preserves underlying structures, minimal scarring[3].

Needle aspiration biopsy

Needle aspiration biopsy involves the use of a fine needle to aspirate cells from a lesion. This technique is commonly used for diagnosing cysts, abscesses, and fluid-filled lesions. The extracted fluid or tissue is then examined under a microscope.

  • Indications: Cysts, abscesses, fluid-filled lesions.
  • Technique: Aspiration of cells or fluid using a fine needle.
  • Advantages: Minimally invasive, useful for fluid-filled lesions[4].

Fine Needle Aspiration (FNA) biopsy

FNA biopsy is similar to needle aspiration biopsy, but it involves using a thinner needle to extract cells from deeper tissue layers. FNA is commonly used to diagnose suspicious nodules, such as thyroid nodules or lymph nodes.

  • Indications: Deep-seated nodules, lymph nodes.
  • Technique: Aspiration of cells using a thin needle.
  • Advantages: Diagnoses deep-seated lesions, minimal scarring.

Choosing the right biopsy approach

Selecting the appropriate biopsy approach depends on factors such as the size, location, and nature of the lesion, as well as the clinical suspicion of malignancy. Dermatologists and healthcare professionals must carefully consider these factors to ensure accurate diagnosis and appropriate treatment planning[5].


Skin biopsies are invaluable tools in dermatology for diagnosing a wide range of skin conditions and diseases. The choice of biopsy approach should be based on a thorough assessment of the lesion and the patient's clinical history. Each type of biopsy has its own advantages and is suited for specific indications. By understanding the different types of skin biopsies and their applications, healthcare professionals can make informed decisions that lead to precise diagnoses and effective treatment strategies, ultimately improving patient outcomes and quality of care.


  1. Lim HW, Collins SA, Resneck Jr JS, et al.The burden of skin disease in the United States.J Am Acad Dermatol. 2017;76(5):958-72.
  2. Indexed at, Google Scholar, Cross Ref

  3. Reeck MC, Chuang TY, Eads TJ, et al.The diagnostic yield in submitting nevi for histologic examination.J Am Acad Dermatol. 1999;40(4):567-71.
  4. Indexed at, Google Scholar, Cross Ref

  5. Heal CF, Raasch BA, Buettner PG, et al.Accuracy of clinical diagnosis of skin lesions.Br J Dermatol. 2008;159(3):661-8.
  6. Indexed at, Google Scholar, Cross Ref

  7. Nischal U, Nischal KC, Khopkar U.Techniques of skin biopsy and practical considerations.J Cutan Aesthet Surg. 2008;1(2):107.
  8. Indexed at, Google Scholar,Cross Ref

  9. Ilyas M, Costello CM, Zhang N, et al.The role of the ugly duckling sign in patient education.J Am Acad Dermatol. 2017;77(6):1088-95.
  10. Indexed at, Google Scholar, Cross Ref

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