Journal of Biotechnology and Phytochemistry

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Short Article - Journal of Biotechnology and Phytochemistry (2021) Volume 5, Issue 3

World Biotechnology 2018: New trends in the treatment of grade II furcation defects using second generation platelet concentrates - Juan Pablo Pava Lozano-National University, Colombia

The furcation defect is defined as the pathological reabsorption of interradicular bone that occurs in multirooted teeth in advanced stages of periodontal disease. Some surgical strategies to cover furcation defects and exposed roots include free gingival grafts, pedicle flaps, subepithelial connective tissue grafts and application of different biomaterial-based grafts. The Platelet Rich Fibrin (PRF) has different characteristics like a high concentration of platelet and leukocytes, as well as fibrin/fibronectin and a low concentration of thrombin that makes flexible its structure, facilitating the uptake of cytokines and migration of other cells involved in the regenerative process. Two furcation defects on 47 and 46 teeth grade I/II (n=2) respectively were evaluated from a healthy male patient 46 years-old who was receiving dental treatment on dentistry Faculty of Antonio Nari?o university. He was treated with coronally displaced flap (CDF) and PRF. A mucoperiosteal partial superficial thickness flap was lifted up from affected teeth and PRF was obtained from a patient blood sample (10mL) in a glass tube without anticoagulant, which was immediately processed. The flap was repositioned to coronal level beyond the cementoenamel line with 2 PRF membranes placed on the root surfaces and sutured. Morphometric and clinical measurement was performed 6 months after the procedure to analyze the interradicular molar zones. RESULTS The CDF with PRF performed showed presence of hard and soft tissues evaluated clinically and tomographically with a significant coverage of p <0.05 in the fornix zones of the molars. On the interradicular area morphometric values shows that tooth 46 there was a decrease (0.0005) of -1.127 (2.104 ? 0.06 vs 0.977 ? 0.07) of defect and tooth 47 (0.0047) of - 0.850 (1.891 ? 0.04) vs 1.041 ? 0.05) CONCLUSION Use of CDF together with PRF can be considered as a treatment option because it achieves a ostensibly osteoconductive, biocompatible function and reduces patient recovery time improving the prognosis of established defects

Author(s): Juan Pablo Pava Lozano

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