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Review Article - Journal of Clinical Pathology and Laboratory Medicine (2024) Volume 6, Issue 1
Therapeutic Drug Monitoring (TDM) from a clinical perspective: Challenges and approaches
The clinical technique of measuring particular pharmaceuticals at predetermined intervals to keep their level in a patient's bloodstream constant and optimize their individual dosing regimens is known as Therapeutic Drug Monitoring. For most drugs, TDM is not necessary; it is primarily used to monitor drugs with limited therapeutic ranges, drugs with significant pharmacokinetic variability, drugs whose target concentrations are challenging to monitor, and drugs that are known to have both beneficial and negative effects. The foundation of TDM is the belief that there is a measurable correlation between dosage and drug concentration in the blood or plasma, as well as between concentration and therapeutic outcomes.
Author(s): Divya.Dara