Otolaryngology Online Journal

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +44-1474-556909

Research Article - Otolaryngology Online Journal (2017) Volume 7, Issue 1

The Relationship Between Tinnitus, Mean Platelet Volume and Neutrophile/Lymphocyte Ratio - Investigation on the new focus of the literature -

Introduction: Tinnitus is a condition that occurs through different pathophysiological mechanisms and its underlying reasons are not completely understood. MPV (mean platelet volume) and nlr (neutrophile/lymphocyte ratio) are the parameters that found to be related to many diseases that cause tinnitus.

Objective: The relationship between MPV, nlr and tinnitus are investigated in this study. According to our observations, this is the first study in literature body that investigates these relationships.

Methods: 80 patients with tinnitus and 41 controls were included in the study. Group 1 consisted of males only, group 2 consisted of females only and group 3 consisted of all patient group regardless of their gender. Only the patients with subjective tinnitus aged 18-65, without any active infection and without diagnosed psychiatric disease were included. Age, MPV, nlr, WBC (white blood cell) and platelet counts were used as parameters of investigation.

Results: Comparison of the referred parameters between the patients and controls in each group were resulted as follows: In group 1; age (p<0.267), WBC (p<0.611), nlr (p<0.053), platelet count (p<0.815) and MPV (p<0.033). In group 2; age (p<0.579), WBC (p<0.209), platelet count (p<0.825), nlr (p<0.066) and MPV (p<0.021). In group 3; age (p<0.600), WBC (p<0.262), platelet count (p<0.363), MPV (p<001) and nlr (p<0.003).

Conclusion: The results of this study suggest a statistically significant relationship between tinnitus and MPV and nlr and may help the further studies on this topic.

Author(s): Ferit Akil, Umur Yollu, Umur Yollu, Muhammed Ayral, Esref Akil

Abstract Full Text PDF