Research Article - Otolaryngology Online Journal (2017) Volume 7, Issue 1
The Relationship Between Tinnitus, Mean Platelet Volume and Neutrophile/Lymphocyte Ratio - Investigation on the new focus of the literature -
Introduction: Tinnitus is a condition that occurs through different pathophysiological mechanisms and its underlying reasons are not completely understood. MPV (mean platelet volume) and nlr (neutrophile/lymphocyte ratio) are the parameters that found to be related to many diseases that cause tinnitus.
Objective: The relationship between MPV, nlr and tinnitus are investigated in this study. According to our observations, this is the first study in literature body that investigates these relationships.
Methods: 80 patients with tinnitus and 41 controls were included in the study. Group 1 consisted of males only, group 2 consisted of females only and group 3 consisted of all patient group regardless of their gender. Only the patients with subjective tinnitus aged 18-65, without any active infection and without diagnosed psychiatric disease were included. Age, MPV, nlr, WBC (white blood cell) and platelet counts were used as parameters of investigation.
Results: Comparison of the referred parameters between the patients and controls in each group were resulted as follows: In group 1; age (p<0.267), WBC (p<0.611), nlr (p<0.053), platelet count (p<0.815) and MPV (p<0.033). In group 2; age (p<0.579), WBC (p<0.209), platelet count (p<0.825), nlr (p<0.066) and MPV (p<0.021). In group 3; age (p<0.600), WBC (p<0.262), platelet count (p<0.363), MPV (p<001) and nlr (p<0.003).
Conclusion: The results of this study suggest a statistically significant relationship between tinnitus and MPV and nlr and may help the further studies on this topic.Author(s): Ferit Akil, Umur Yollu, Umur Yollu, Muhammed Ayral, Esref Akil