Review Article - Current Trends in Cardiology (2020) Volume 4, Issue 2

Sudden death and hypertrophic cardiomyopathy: A review.

Hypertrophic cardiomyopathy is a genetic disease that affects the cardiac sarcomere, resulting in myocardial hypertrophy and disarray. Affected patients have a predisposition for malignant ventricular tachyarrhythmias and, consequently, sudden cardiac death. With the availability of therapeutic measures that prevent sudden death, the identification of high-risk patients is now of greater importance. The clinical electrophysiological study is of limited use for stratifying these patients. More recently, increased attention has been given to the degree of echocardiographically documented left ventricular hypertrophy and prognostically significant genetic mutations. Once a high-risk patient is identified, prophylactic treatment is warranted. Tools are now available to identify and treat high-risk patients with hypertrophic cardiomyopathy Author(s): Claudia da Silva Fragata

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