Short Communication - Virology Research Journal (2022) Volume 6, Issue 1

Significant role of HIV gp120 envelope glycoprotein.

The passage of human immunodeficiency infection (HIV) into cells requires the consecutive interaction of the viral outside envelope glycoprotein, gp120, with the CD4 glycoprotein and a chemokine receptor on the cell surface. These intuitive start a combination of the viral and cellular layers. In spite of the fact that gpl20 can inspire virus-neutralizing antibodies, HIV escapes the resistant framework. We have illuminated the X-ray precious stone structure at 2.5 Å determination of an HIV-1 gp120 center complexed with a two-domain part of human CD4 and an antigen-binding part of a neutralizing counter acting agent that pieces chemokine-receptor official.

Author(s): Alessandro Esposito*

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