Virology Research Journal

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Rapid Communication - Virology Research Journal (2022) Volume 6, Issue 5

Potential biomarker of disease activity of systemic chronic active adeno-associated virus gene therapy

The use of vectors based on the small parvovirus adeno-associated infection has picked up critical force amid the past decade. Their tall productivity of transduction of post mitotic tissues in vivo, such as heart, brain, and retina, renders these vectors amazingly alluring for a few quality treatment applications influencing these organs. Other than utilitarian redress of distinctive monogenic maladies, the plausibility to drive effective and diligent transgene expression within the heart offers the plausibility to create imaginative treatments for predominant conditions, such as ischemic cardiomyopathy and heart failure. Therapeutic genes are not only restricted to protein-coding complementary DNAs but moreover incorporate brief clip RNAs and microRNA qualities, hence broadening the range of conceivable applications.

Author(s): Jayden Connor*

Abstract Full Text PDF

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