Journal of Advanced Surgical Research

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Editorial - Journal of Advanced Surgical Research (2021) Volume 5, Issue 1

Non-alcoholic fatty liver disease

Non-Alcoholic Fatty Liver Disease (NAFLD) is a serious public health concern across the world. NAFLD (including simple steatosis and steatohepatitis) is defined by changes in hepatic lipid metabolism, which can progress to serious liver consequences such as cirrhosis and hepatocellular cancer. As a result, a thorough assessment of lipid abnormalities in NAFLD patients' livers is critical. Lipidomics systems based on mass spectrometry enable in-depth investigation of lipid changes in a variety of human illnesses, including NAFLD. This review summarises current research on lipid alterations associated with NAFLD and related complications, with a focus on changes in long-chain and short-chain fatty acid levels in both serum and liver tissue, as well as hepatic expression of genes encoding the enzymes that catalyse lipid interconversions

Author(s): Hazel Smith

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