Review Article - Asian Journal of Biomedical and Pharmaceutical Sciences (2021) Volume 11, Issue 81
In-silico pharmacological studies and RMSD comparison of FDA drugs with bioactive compounds in musa paradisica for ligand promotion.
This study includes Bio-Pharmaceutical research for atomic demonstrating techniques, inside an assortment of medication revelation programs, to examine complex organic and compound frameworks. The coordination of computational and test procedures has been of extraordinary incentive in the distinguishing proof and advancement of novel promising mixes. Comprehensively utilized in a present-day drug plan, sub-atomic docking techniques investigate the ligand compliances received inside the coupling locales of macromolecular targets. We are considering Musa species for our medication revelation measure by utilizing bioinformatics programming like Chemspider, Swiss ADME, Swiss prediction to find out the analogues of a particular compound following their related physicochemical properties including both primary and secondary properties for the structure-based medication plan. Finally leading to evaluate the suitable drug compound present in Musa species for the drug design using Computer-Aided Drug Design (CADD).Author(s): Rakesh N R, Gurumurthy H, Pradeep S, Kumar H M, Harshitha, Yashaswini