Asian Journal of Biomedical and Pharmaceutical Sciences

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Research Article - Asian Journal of Biomedical and Pharmaceutical Sciences (2022) Volume 12, Issue 91

Evaluate the safety and efficacy of antibiotics in postoperative Hernioplasty and Herniorrhaphy.

Aim: To evaluate the safety and efficacy of antibiotics in post-operative Hernioplasty and Herniorrhaphy. Objectives: Assessing the clinical efficacy of post-operative antibiotics like ceftriaxone, amikacin and piperacillin plus tazobactam in reducing surgical site infections. By measuring the wound status of patients by using wound grading during postoperative follow up intervals. To determine social demographic details and categoric the types of hernia in study population. Methods: This is a prospective observational study performed and conducted at General surgery department, Government General Hospital, Kurnool. Individual were analyzed by particulars of age, sex, date of admission and date of surgery, investigations, past history, comorbid conditions like hypertension, diabetes etc., patients were selected on the basis of inclusion and exclusion criteria. Results: A totals of 58 patients the distribution of male (75.8%) and female (24.1%). The majority of type of hernia is direct inguinal hernia of 17(29.3%) when compared to all types of hernias. The administration of post-operative antibiotics like ceftriaxone + metronidazole, piperacillin/ tazobactam + metronidazole, ceftriaxone + metronidazole + amikacin and sulbactam sodium + cefoperazone sodium + metronidazole, is markedly reduced surgical site infections. Wound grades in post-operative patients were comes under grade 0 was more compared to grade1 and grade 2. Conclusion: In this study the different groups of antibiotics like cephalosporin’s, Anti protozoal drugs and aminoglycosides in post-operative surgeries are showing equal effectiveness in reducing surgical site infection in both comorbid and noncomorbid conditions.

Author(s): Shaik Shabana Tahaseen*, Bogyam Bhavana, Veldurthi Hari Sushma, L Grace

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