Allied Journal of Medical Research

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Commentary - Allied Journal of Medical Research (2022) Volume 6, Issue 12

Effects of SARS-CoV-2 mutations on the pathogenicity, structure, and function of the virus.

The COVID-19 outbreak, the third coronavirus pandemic, recently started in China. SARSCoV-2, the most recent coronavirus to be identified, is the sixth coronavirus to affect humans. Acute heart damage, severe pneumonia and RNAaemia together with glass turbidity are the major pathophysiology of SARS-CoV-2 infection. It has a single-stranded, 60-140 nm-diameter, 26-32 kbp-sized positive-sense RNA genome. Spike glycoprotein functions as the principal cell receptor for the membrane-bound aminopeptidase known as ACE2, which is responsible for viral pathogenesis. It has been established that a number of variables, including differing national quarantine laws and diverse racial or genetic backgrounds, may have an impact on the COVID-19 infection and fatality rates in specific regions.

Author(s): Adam Emma

Abstract Full Text PDF

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