Journal of Clinical Research and Pharmacy

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Abstract - Journal of Clinical Research and Pharmacy (2021) Volume 4, Issue 1

Determination of 2-Mercaptoethanol by Potentiometric Titration with Mercury (II) Chloride



  A new, direct, rapid, simple, sensitive and accurate method for the determination of 2-Mercaptoethanol (Quick facts) or Mercury(II); The method is based on the using mercury (II) chloride solution as titrant (or reverse) in potentiometric titration depending on the first and second derivative differential procedure was used for all titrations; The method is suitable for the assay of 2-ME in micro amounts at a wide range of mass (15626.6-7.8133 µg) in 80 mL; The equivalence point is marked by a sharp peak in all instances and molar ratio of (Hg2+: 2-ME) at inflection point (1:2). Accurate and precise results were obtained with an average error % of (0.1333-0.5667%) and a Relative Standard Deviation of (0.70499-0.1957%) respectively.


Author(s): Ali Rasool Mahmood Albakaa

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