Asian Journal of Biomedical and Pharmaceutical Sciences

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Research Article - Asian Journal of Biomedical and Pharmaceutical Sciences (2019) Volume 9, Issue 66

Bacterial Etiology of Community Acquired Pneumonia and their Antimicrobial Susceptibility in Patients Admitted to Alshaab Teaching Hospital, Sudan.

Background: Community Acquired Pneumonia (CAP) is a frequently encountered lower respiratory tract parenchymal lung infection which continues to be a major health problem leading to significant morbidity and mortality worldwide.

Objective: This study was aimed to determine frequency and susceptibility pattern of bacterial etiology of community acquired pneumonia isolates from Sudanese patients.

Materials and methods: One hundred Sputum specimens were collected from patients with Community Acquired Pneumonia attended to chest unit in Alshaab Teaching Hospital during the period between Januarys to March 2017. The patients were grouped according their age as follows (year); 16 to 26, 27 to 37, 38 to 48, and 49 to 60.Antibiotic susceptibility test of isolated organisms were carry out by the Kirby- Baur disc diffusion method.

Results: Out of 100 patient enrolled in the study the etiology was identified in 42/100 (42%) with most frequent isolates Klebsiella pneumoniae 18/42 (42.8%) followed by: Pseudomonas aeruginosa 13/42 (30.9%), Staphylococcus aureus 10/42 (23.9%) and Escherichia coli 1/42 (2.4%). Only 3 (16.7%) organisms among all isolated Klebsiella pneumoniae were found resistant to all investigated antibiotic (third generation cephalosporin (3GC)) 6/10 (60%) from all isolated Staphylococcus aureus found resistant to methicillin (ME 10 μg) and Oxacillin (OX 1 μg). All isolated Pseudomonas aeruginosa were sensitive to Meropenem. The isolated Escherichia coli found only resistant to Ampicillin.

Conclusion: Prevalence of community-acquired pneumonia in adult Sudanese patients is relatively high with major causative agents Klebsiella pneumoniae.

Author(s): Ibrahim AI, Hassan AA, Ahmed OA, Daffalla SO

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