Research Article - Asian Journal of Biomedical and Pharmaceutical Sciences (2019) Volume 9, Issue 68
Asymptomatic Plasmodium falciparum malaria infection in University undergraduate students
Background: Malaria infection still remains a notable health problem in resource-limited countries
due to difficulties in the implementation of control measures.
This was a prospective study designed to assess the prevalence of asymptomatic P. falciparum malaria
infection in premedical undergraduate students at Nnamdi Azikiwe University Nnewi, Nigeria.
Methods: A total of 180 consenting apparently healthy subjects (male=90), female=90) aged 18-30
years were randomly recruited for this study. One millimeters of blood sample was collected from each
of these participants and dispensed into EDTA bottle for P.falciparum malaria parasite screening
using thick and thin film Giemsa staining technique and HRP2Pf rapid antigen diagnostic test kit
(Access Bio Inc., USA).
Results: Ninety nine (99) of these participants tested positive for asymptomatic P. falciparum malaria
giving a prevalent rate of 55% while 81 subjects were uninfected and served as control The prevalence
was higher in males (54.5%), underweight (46.5%) (P<0.0001) and among students aged 18-21 years
(48.5%) followed by overweight (30.3%) students (P=0.039). Only (33.9%) of all the students used
insecticide treated net (ITNs) (P=0.008).
Conclusions: The present study showed high prevalence rate of asymptomatic P. falciparum malaria
infection among university students who continuously served as reservoir for transmission to the
uninfected ones which might progress to disease severity if left untreated. Author(s): Ukibe Nkiruka Rose*, Ukibe Solomon Nwabueze, Onwubuya Ikechukwu Emmanuel, Ofia Anya Kalu
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