Journal of Cardiovascular Medicine and Therapeutics

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Pulmonary embolism associated with renal cell carcinoma

*Corresponding Author:
George Trantalis, M.D.
Health Center of Kalivia Kalivia - 19010, Attiki Greece
Tel: 203 974 7892
E-mail: dawn.foster@yale.edu

Accepted date: March 24, 2017

Citation: Trantalis G, Gikas A, Toutouzas K. Pulmonary embolism associated with renal cell carcinoma. J Cardiovasc Med Ther. 2017;1(1):5-6.

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Kidney cancer is the third most common urological cancer, accounting for 3.5% of newly diagnosed cancers. We demonstrate the case of a 75-year-old man, who presented with acute dyspnea (the ejection fraction was 20%). He had coronary disease and, ten years previously, had undergone coronary artery bypass grafting. Following a number of diagnostic examinations, the patient was diagnosed with pulmonary embolism. After initiation of Enoxaparin administration, the clinical symptoms were significantly improved. Abdominal ultrasound examination showed the presence of a thrombus in the inferior vena cava (IVC) (Figure 1). This finding was confirmed by a MRI (Figures 2A and 2B). Histopathology revealed it to be renal cell carcinoma.

 

cardiovascular-medicine-therapeutics-Abdominal-ultrasound-thrombus-IVC

Figure 1: Abdominal ultrasound shows a thrombus within the IVC.

cardiovascular-medicine-therapeutics-MRI-views-tumor-thrombu-IVC

Figure 2a and 2b: MRI views of the tumor thrombus inside the IVC.

Kidney cancer tends to invade the venous system, especially the renal vein and/or the IVC. It is estimated that 4% to 10% of renal cancers form a tumor thrombus within the local venous circulation, where about 1% of them extending into the right atrium.