Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article - Biomedical Research (2016) Volume 0, Issue 0

The association between serum vitamin D status and gait ability in young adults

The purpose of the present study was to examine whether serum vitamin D status is associated with a change in gait speed in young adults. In this cross-sectional study, 60 young adults aged ≥ 19 years (36 female and 24 male participants) were recruited from the general population. Spatiotemporal parameters of gait were assessed by using a validated wireless inertial sensing device. The blood vitamin D status was classified as deficiency (<12.5 ng/ml), insufficiency (≥ 12.5 ng/ml to <20 ng/ml), and sufficiency (≥ 20 ng/ml). Linear increases in physical performance parameters such as grip strength, gait speed, stride length, and High-Density Lipoprotein Cholesterol (HDL-C) were found across the incremental categories of serum 25-hydroxyvitamin D (25(OH)D). A significant positive association was observed between serum 25(OH)D levels and HDL-C (r=0.759, P=0.001), grip strength (r=0.329, P=0.011), gait speed (r=0.873, P=0.001), stride length (r=0.690, P=0.001), and swing phase (r=0.322, P=0.013). A decline in gait speed was more likely to be associated with serum 25(OH)D deficiency (Odds Ratio: (OR), 13.1; 95% Confidence Interval (CI), 3.84-45.02; adjusted OR, 13.9; 95% CI, 3.61-53.7). To our knowledge, this cross-sectional study is the first to report that higher serum 25(OH)D levels are associated with gait ability and lipid parameters in young adults. Multiple regression analysis showed that vitamin D status is an independent predictive factor for a decline in gait speed.

Author(s): Jong-Hwan Park

Abstract Full Text PDF