Biomedical Research

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Prevalence and distribution of high-risk human papillomavirus in amasya region, Turkey.

Aim: In this study, the aim is to determine the HPV DNA prevalence and the genotype distribution of High Risk HPVs in women who came to Amasya Cancer Early Diagnosis, Screening and Education Center (KETEM) for screening.

Materials and methods: Totally 7992 women between the ages of 30-65 were included in the study between August, 2014 and August, 2015. HC II HPV DNA test (Digene Corporation, Gaithersburg, MD, USA) was used and HPV DNA presence and HR-HPV type detection studies were performed by using cervical swab samples.

Results: According to our results, 2.7% of the cases were HPV-DNA positive. HPV positivity was detected mostly in women who were between the ages of 30-39 years. In the genotype distribution of HPV positive women, most frequently observed type was HPV16 (23.6%) and then HPV51 was observed with 9% frequency. HR-HPV rates were detected as 77.8% in all HPV positive women.

Conclusion: HPV DNA positivity rate was low in our province. However, the high positivity of HR-HPV types detected in HPV positive women let us think that these women should be more careful in their future controls and routine screenings in terms of cervical cancer.

Author(s): Ridvan Güçkan, Çetin Kilinç, Elif Gözdemir, Atiye Aysemin Gürçaglar, Öner Nergiz