Case Report - Journal of Clinical Pathology and Laboratory Medicine (2018) Volume 2, Issue 1
Plasmablastic lymphoma presenting as a large cervical-thoracic mass: Report of a case and literature review.
Plasmablastic lymphoma (PBL) was first described in the jaws and the oral cavity of human immunodeficiency virus infected patients. This subtype of lymphoma is considered as a variant of the diffuse large B-cell lymphoma with a phenotype of plasma cell differentiation that expresses markers such as CD38, CD138 and MUM1 protein. HIV- associated PBL is associated with an aggressive clinical course, poor prognosis and shot survival even in the era of highly active antiretroviral therapy (HAART). Primary soft tissue Non-Hodgkin lymphomas (NHL) are very rare and account only the 0.1% of the cases. Generally, NHL of the soft tissue present as large subcutaneous masses, with fast growing and without evidence of nodal or skin involvement. Here we describe a primary NHL of the soft tissue in an HIV infected patient.Author(s): Marcelo Corti, Luis De Carolis, Jorge Correa, Ana Campitelli, Marina Narbaitz