Biomedical Research

Research Article - Biomedical Research (2017) Volume 0, Issue 0

Observations on the effect of autogenous arteriovenous fistula and cuffed and tunneled catheter vascular access in clinical application of hemodialysis

Purpose: Autogenous arteriovenous fistula and cuffed and tunneled catheter these two different vascular accesses were adopted in patients’ hemodialysis for contrastive analysis research on its treatment clinical effect.

Methods: A total of 78 patients in our hospital requiring for long-term hemodialysis were divided into 2 groups through random digit distribution method, autogenous arteriovenous fistula (AVF) group and cuffed and tunneled catheter (CTC) group respectively, 39 for each group; venous blood samples were taken after dialysis, and each biochemical index is detected by automatic biochemical analyzer, conducting contrastive analysis on urea clearance index (Kt/V), recirculation rate and complication incidence of two groups respectively after dialysis.

Results: Blood urea nitrogen (BUN) and Scr indices were in significant downward trend for two groups after dialysis compared with those before dialysis, with significant difference (P<0.05), and there was no statistical significance (P>0.05) comparing with each index (Hb, plasma-albumin (Alb), total protein(TP), CRP) group after dialysis. Kt/V and recirculation rate levels of Architectural vulnerability factor (AVF) group increased obviously after dialysis compared with CTC group, and the complication incidence was lower than that of control group significantly.

Conclusion: Adopting autogenous arteriovenous fistula vascular access for hemodialysis had more significant effect than that of cuffed and tunneled catheter and less complication, and it had greater clinical advantages, which is worth learning.

Author(s): Guoxin Zhang, Lanfen Xue, Min Chen, Jianbin Gu, Xueping Wang

Abstract Full Text PDF