Biomedical Research

Journal Banner

Investigation of serum 25 hydroxy vitamin D level in critically ill children and its relation with demographic and clinical risk factors

Background: Vitamin D is a pleiotropic hormone important for the proper functioning of multiple organ systems. It has been hypothesized that vitamin D deficiency could contribute to mortality, disorders, or worsen outcomes in critical illness. The aim of this study was to investigate the relation of vitamin D deficiency with potential demographic and clinical factors.

Methods: Eighty two children hospitalized in ICU section of Children’s Medical Center were contributed into this study and serum level of vitamin D was extracted from patients’ file.

Results: The level of vitamin D significantly decreased from 37.9532 to 23.8771 ng/mL. Logistic regression analysis, also, confirmed the relation between age and vitamin D serum level. This change probably was because of higher growth rate among children older than 2 years. So, vitamin D should be added to the older children’s nourishment.

Author(s): Bahare Yaghmaie, Fatemeh Sayarifard, Mohammadreza Modarresi, Masoud Mohammadpour, Meysam Sharifzade, Abbas Hassani, Abbas Rahimi Foroushani, Parisa Khalili, Bahar Allahverdi