Research Article - Biomedical Research (2018) Volume 29, Issue 1
Identification of signals mediated the treatment of cancer by curcumin extract
Background: The plant polyphenols play a vital role in human diets that link to health and resilience evolutionarily and mechanistically.
Materials and Methods: The rational of this study to identify the signals mediated the treatment of cancer by curcumin extract.
Results: Different cancer cell line will be used for detection of the signal molecules of apoptotic during treatment with Methanol Extract of Curcumin (MEC). Hep2G and HeLa cell lines were used treated with 10, 20 and 40 μl of MEC. Analysis of MEC by GC/MS referred presence of 1, 3, 5-benzenetriol as active ingredients. In vitro study, the anticancer activity of 1, 3, 5-benzenetriol were 87% and 85% for HeLA and HepG2 respectively.
Conclusion: Curcumin as an efficient medicinal displayed a significant effect on HeLa and HepG2 cells which is very effective in the treatment of cancer this is due to presence of 1, 3, 5-benzenetriol.Author(s): Jehan A. Khan