Biomedical Research

Research Article - Biomedical Research (2017) Volume 0, Issue 0

Difference of thyroid hormone reference ranges in diagnosis of thyroid functions between normal pregnant women in the early, middle and late pregnancy and normal adults

Objective: To discuss and analyze the difference in thyroid hormone reference ranges between normal pregnant women and normal adults, and study the thyroid dysfunction in pregnant women during pregnancy.

Methods: Blood samples of 166 pregnant women and 50 non-pregnant women were randomly collected, to detect Thyroid Stimulating Hormone (TSH), Free Triiodothyronine (FT3), Free Thyroxine (FT4), Total Triiodothyronine (TT3) and Total Thyroxine (TT4).

Results: The ratio of thyroid dysfunction was 9.64% (16/166) by using normal thyroid hormone reference ranges of pregnant women as an index, while the ratio of thyroid dysfunction was 1.20% (2/166) by using the normal thyroid hormone reference ranges of non-pregnant women as an index. The difference in thyroid hormone reference ranges between the two methods was statistically significant (P<0.05).

Conclusions: There were significant differences in thyroid hormone levels between pregnant women and non-pregnant women, and between women during different stages of pregnancy, and the ratio of thyroid dysfunction during pregnancy was 9.64%; therefore, thyroid function screening is necessary in all pregnant women.

Author(s): Qian Fang, Wang Jun, Lv Honglei

Abstract Full Text PDF