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De novo thyroid cancer after liver transplantation

Introduction: The occurrence of de novo thyroid cancer following liver transplantation was rare. We reported our case to explore the clinical features, risk factors and preventive measures against the incidence of de novo thyroid carcinoma after hepatic transplantation.

Case report: This was a single case report. One female patient, aged 55 years old, undergoing allogeneic piggyback liver transplantation in combination with venacavaplasty and had de novo thyroid cancer subsequent. A palpable solid tumor with clear margins approximately 2 cm × 1 cm × 1 cm in size was detectable in the right neck. She underwent radical thyroidectomy, cervical lymph node dissection combined with exploratory operation. After receiving combined surgeries, she displayed stable vital signs and normal cardiopulmonary function, had no signs of hoarseness, difficulty in drinking or hand/ mouth numbness, etc. The patient was well recovered after postoperative 2-month follow-up.

Conclusion: The clinical and histopathological data were collected to analyse the clinical features, risk factors and preventive measures against the incidence of de novo thyroid carcinoma after hepatic transplantation.

Author(s): Chen Li, Wen Tian, Yu Zang, Bin Zhou, Lin Chen