Biomedical Research

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Curative effect comparison of anterior and posterior approach in debridement combined with bone graft fusion for the treatment of spinal tuberculosis

Objective: To compare the curative effect of anterior or posterior approach debridement conbined with bone graft fusion in treatment of spinal tuberculosis.

Methods: 92 cases of thoracic and lumbar tuberculosis patients in our hospital were collected in recent 3 years. All patients were randomly divided into two groups (Group A and B), 42 cases in each group. The patients of Group A and B were respectively treated with anterior or posterior debridement conbined with bone graft fusion. Comparing the clinical efficacy in the two groups.

Results: There was no significant difference in the time of operation, the intraoperative and postoperative bleeding volume, and hospital stays after operation in the two groups (P>0.05). After surgery, nerve function, mean Cobbs of the two groups of patients, VAS score, erythrocyte sedimentation rate were significantly improved compared with before operation (P<0.05). And the B group of kyphosis correction rate was significantly higher than A group (x2=5.446 P=0.019), meanwhile the improvement of VAS score (x2=9.237 P<0.001) and the time of recovery of ESR (x2=7.005 P<0.001) group was significantly better than group A.

Conclusion: Compared with the anterior approach, posterior approach for correction of kyphosis was higher, the pain improvement and erythrocyte sedimentation rate of the effect is more obvious, and less traumatic, so the posterior surgical treatment is relatively better.

Author(s): Jun-ming Cao, Liu Yang, Yong-sheng Lin, Zhi-hong Wang, Yi-peng Yang, He-huan Xia