Evaluation of lymph nodes is an integral part in the management of women with gynecologic cancers, which is why the pelvic and aortic lymphadenectomy is widely used as a staging and/ or prognostic procedure in such malignancies. The purpose of this study was to describe our experience with pelvic and aortic laparoscopic lymphadenectomy and evaluate the safety and feasibility of this procedure for gynecologic malignancies. From January 2004 to December 2015, a laparoscopic pelvic and/or aortic lymphadenectomy was performed in 372 women at the Department of Gynecology Oncology of the University General Hospital of Castellon and at the Department of Obstetrics and Gynecology of Sant Pau and Santa Tecla Tarragona Hospitals. Out of the 372 cases, 240 combined pelvic and paraaortic lymphadenectomies were performed, while 108 and 24 patients underwent pelvic and aortic lymphadenectomy respectively. The mean operative times were 40 min (20-89) in order to perform a complete pelvic lymphadenectomy, 62 min (21-151) for transperitoneal aortic lymphadenectomy and 45 min (35-65) for a retroperitoneal approach. A conversion to laparotomy was needed in 1.6% of patients. Twenty-three (6.1%) complications were encountered in 372 patients undergoing laparoscopic lymphadenectomy. Nine (2.4%) major complications occurred intraoperatively while fourteen (3.7%) appeared postoperatively. The most frequent intraoperatory complication was vascular injury (1.3%). Laparoscopic lymphadenectomy can be considered a safe and achievable procedure, and could be considered the golden standard procedure for staging gynecologic malignancies.