Research Article - Biomedical Research (2018) Volume 29, Issue 3
Comparing the effect of adding dexmedetomidine and tramadol to lidocaine 5% in elongating the period of post-operative analgesia in spinal anesthesia
Background: The aim of this study was to compare addition of dexmedetomidine and tramadol to lidocaine 5% in the period of postoperative analgesia of spinal anesthesia among women candidated for caesarean.
Methods: This double-blind clinical trial conducted on women applying for elective caesarean. Two hundred and ten women were participated in this research and they randomly divided into dexmedetomidine, tramadol and placebo groups. The pain scale, length of analgesia and the average amount of the drug taken within 24 h, after postoperative nausea, vomiting and shivering measured.
Results: No significant difference was observed among the two gropus on pain score, length of postoperative analgesia, the amount of drug, postoperative nausea, vomiting and shivering (P ≥ 0.05).
Conclusion: Taken together, dexmedetomidine and tramadol were beneficial compared to the placebo. Therefore it may be utilized to reduce pain in caesareans.Author(s): Alireza Kamali, Maryam Shokrpour, Aminlu Radmehr, Shirin Pazuki