Biomedical Research

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Clinical analysis of 14 cases of community-acquired Pseudomonas aeruginosa bacteraemia in children

This aims to study the clinical features and outcomes of Community-Acquired Pseudomonas aeruginosa Bacteraemia (CAPAB) in children. Retrospectively analysed the conditions of patients diagnosed with sepsis over nearly 6 years and screened out 14 cases of CAPAB in children to statistically analyse the related clinical features, biochemical tests, susceptibility results, and treatment outcomes. There were 7 boys and 7 girls among the 14 Community-Acquired Pseudomonas aeruginosa Bacteraemia (CAPAB) children with an average age of 21.8 months. Community-Acquired Pseudomonas aeruginosa Bacteraemia (CAPAB) occurred mainly in spring and winter, and all participants exhibited fever symptoms with an average course of 6.1 days. Most cases were associated with digestive symptoms, and 4 exhibited necrotic abscess-like rash changes. No child received effective antibiotic treatment before admittance, 9 progressed to septic shocks, and 7 died; the mortality rate was 50%. Community- Acquired Pseudomonas aeruginosa Bacteraemia (CAPAB) incidence in children was low and was more associated with fever and digestive symptoms. Necrotic abscess-like rash was the specific change, and shock might have progressed rapidly and resulted in high mortality.

Author(s): Tao Zhang, Jiujun Li, Xiaoshi Zheng, Lijie Wang, Zhijie Zhang