Objective: The study aimed to assess the relationship between Body mass index (BMI), body fat percentage(BFP) and waist hip(WH) ratio in predicting Pre-Diabetes and Pre- Hypertension. Methods: A total of 389 adolescents aged 11–17 years were recruited from Doddaballapura government school. Body Mass Index and Waist Hip Ratio were determined using standard equipment’s. Body fat percentage was derived from a body fat analyser. Fasting blood glucose was determined by glucometer method, Blood pressure was recorded using sphygmomanometer. Results: Compare to students with normal BMI, those who are overweight had 7.19 times [95% CI: (2.25-22.96)] high odds to have pre hypertension or hypertension. Similarly compare to normal BMI students, obese students were 28.76 times high odds [95% CI: (2.5-330.27)] to have pre hypertension or hypertension. There was no significant difference between normal BMI students and underweight students in terms of Pre hypertension/ Hypertension. Compare to students with normal WH ratio, low WHR students didn’t have any significant correlation in developing Pre hypertension or hypertension. Compared to students with normal Body fat percentage, those who had a high BFP were 6.02 times high odds to have pre hypertension or hypertension similarly those who had very high BFP were 21.25 times high odds to have pre hypertension or hypertension in respect to predicting pre diabetes, BMI and waist to hip ratio were not significantly correlated, whereas high Body fat percentage had 1.46 high odds as compared to normal BFP. Conclusion: These data suggest the importance of the BMI, Body fat percentage and waist to hip ratio in adolescents, in prevention and early intervention of Obesity, Hypertension and Pre-diabetes since it may be the most cost-effective way of reducing the complications related with them.