Biomedical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article - Biomedical Research (2017) Volume 0, Issue 0

Application of diffusion weighted imaging in the diagnosis of bone metastases from lung cancer

Objective: To investigate the application of background inhibition of fast systemic magnetic resonance diffusion imaging (DWI) in bone metastasis of lung cancer.

Methods: Fifty healthy volunteers and 57 patients with lung cancer diagnosed by pathology were examined by WB-DWI, and reconstructed by 3D-MIP and black-and-white flip-flop. The skeletal system was divided into 8 regions, and the number of WB-DWI positive cases in each region was recorded. All WB-DWI images were compared with positron emission computed tomography (PET-CT) images.

Results: There were 45 WB-DWI-positive cases and 207 lesions in 85 affected areas. There were 47 PET-CT positive cases and 87 involved lesions. The total number of lesions were 197.

Conclusion: The consistency of WB-DWI and PET-CT is very good, and WB-DWI is fast, cheap, non-radioactive and has good reproducibility. Therefore, it has significant clinical value in the diagnosis and treatment follow-up of lung cancer.

Author(s): Wei Zuo, Wei Zhang

Abstract Full Text PDF