Biomedical Research

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Anti-Mullerian hormone as an examination for ovulatory dysfunction of female

Objective: To investigate the relationship between anti-mullerian hormone (AMH) and ovulatory dysfunction.

Methods: The enzyme-linked immunosorbent assay (ELISA) was used to detect the serum level of AMH, the estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), the progestin (P), and the testosterone (T) in 106 participates with infertility (observation group)and carried on comparing with 102 women with pre-pregnancy physical examination (control group)Data were statistically analyzed.

Results: The serum hormone levels of AMH and LH in the observation group were higher than those in the control group (P<0.05). The FSH level of observation group was obviously lower than that in the control group (P<0.05). Pearson correlation analysis showed positive relationship between serum AMH and LH (P<0.05) as well as T (P<0.05). Serum AMH level in the observation group was negatively collated with FSH (P<0.05). No significant relationships were found between serum AMH and E2 level.

Conclusion: This study suggests that serum AMH level was associated with abnormal follicular development and would an effective measurement for ovulatory dysfunction of sterile female.

Author(s): Liu Honglian, Hong Li