Research Article - Biomedical Research (2017) Volume 28, Issue 4
Analysing the therapeutical action of lung recruitment maneuver on patients with acute respiratory distress syndrome by comparing different ventilation strategies
Introduction: This study is to analyse the therapeutical action of Lung Recruitment Maneuver (LRM) on patients with Acute Respiratory Distress Syndrome (ARDS) by comparing different ventilation strategies.
Methods: In control group, patients’ Positive End-Expiratory Pressure (PEEP), in Synchronized Intermittent Mandatory Ventilation (SIMV) plus PEEP model, were increased successively with the levels of 5 cm H2O, 10 cm H2O and 15 cm H2O, and 60 min duration ventilation in every level. On the basis of control group, in test group excepting for LRM in the beginning of each level, SIMV plus PEEP model was taken, and patients’ PEEP also increased successively with the levels of 5 cm H2O, 10 cm H2O and 15 cm H2O, and 60 min duration ventilation in every level. Blood gas analysis was performed for patients. Oxygenation index (PaO2/FiO2), partial pressure of arterial carbon dioxide (PaCO2), blood oxygen pressure (PaO2), QS pulmonary shunt (Qs/Qt) and saturation of blood oxygen (SpO2) were taken statistically and calculated.
Results: In test group, after lung recruitment maneuver, patients’ SpO2, PaO2, PaO2/FiO2 and Qs/Qt were improved significantly (P<0.05). PaCO2 of patients in two groups had significant difference only when PEEP was 10 cm H2O, while in other levels the differences did not have significant difference (P>0.05).
Conclusion: LRM has remarkable curative effect on maintaining alveolar dilatation and improving pulmonary ventilation.Author(s): Pu Zhao, Junfeng Yang, Yi He