Neurophysiology Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (629)348-3199

Short Communication - Neurophysiology Research (2023) Volume 5, Issue 4

Understanding optic neuritis: Symptoms, causes, and treatment

Zhiqiang Qiu *

Department of Ophthalmology, Sun Yat-sen University, Guangzhou, China.

*Corresponding Author:
Zhiqiang Qiu
Department of Ophthalmology,
Sun Yat-sen University
Guangzhou, China

Received:07-Jul-2023, Manuscript No. AANR-23-110611;Editor assigned: 10-Jul-2023, PreQC No. AANR-23-110611 (PQ);Reviewed:24-Jul-2023, QC No. AANR-23-110611;Revised:26-Jul -2023, Manuscript No. AANR-23-110611 (R); Published:02-Aug -2023, DOI: 10.35841/ aanr-5.4.156

Citation: Zhiqiang Qiu. Understanding optic neuritis: Symptoms, causes, and treatment. Neurophysiol Res. 2023; 5(4):156

Visit for more related articles at Neurophysiology Research


Optic neuritis is a relatively rare but significant eye condition that can cause sudden vision problems and discomfort. It occurs when the optic nerve, which transmits visual information from the eyes to the brain, becomes inflamed. While optic neuritis can affect people of all ages, it is most commonly diagnosed in young adults, particularly those between the ages of 20 and 40. This article explores the symptoms, causes, diagnosis and treatment options for optic neuritis.

Symptoms of optic neuritis:

One of the hallmark symptoms of optic neuritis is a sudden and often painful loss of vision. This loss of vision is usually experienced in one eye and it can range from mild blurriness to complete blindness. Other common symptoms include a decrease in colour perception, particularly red and green tones, as well as increased sensitivity to light and visual disturbances like flashing lights or dark spots. Some individuals may also experience pain when moving the affected eye [1].

Causes of optic neuritis:

The exact cause of optic neuritis is not always clear, but it is often linked to autoimmune processes. It is believed that the immune system mistakenly attacks the protective covering (myelin) of the optic nerve, leading to inflammation and damage. This is often associated with demyelinating diseases such as Multiple Sclerosis (MS), a chronic autoimmune disorder that affects the central nervous system. However, not all cases of optic neuritis are associated with MS. Other potential causes of optic neuritis include viral infections, such as the Human Herpes Virus 6 (HHV-6) and the Epstein - Barr Virus (EBV). In rare cases, bacterial infections or other inflammatory conditions can trigger optic neuritis as well [2].


If an individual experiences sudden vision problems or any of the aforementioned symptoms, it is crucial to seek immediate medical attention. An ophthalmologist or neurologist will typically conduct a comprehensive eye examination and review the patient's medical history to make an accurate diagnosis. One of the key diagnostic tools for optic neuritis is an MRI scan, which can help visualize the optic nerve and detect any inflammation or damage. Lumbar puncture (spinal tap) may also be performed to analyze the cerebrospinal fluid for signs of inflammation or the presence of specific antibodies associated with conditions like multiple sclerosis[3].


The treatment approach for optic neuritis aims to alleviate symptoms, reduce inflammation and prevent future episodes. In cases where the cause is associated with an underlying condition, such as multiple sclerosis, treating the underlying disease is an important part of managing optic neuritis. Corticosteroids either administered orally or intravenously, are commonly used to reduce inflammation and speed up the recovery process. These medications work by suppressing the immune response that contributes to the inflammation of the optic nerve. Most individuals with optic neuritis experience significant improvement in their vision after a course of corticosteroid treatment [4].


The prognosis for optic neuritis varies from person to person. Many individuals experience a partial or complete recovery of their vision within a few weeks to months after the onset of symptoms. However, some may be left with residual visual deficits, especially if the inflammation has caused irreversible damage to the optic nerve [5].


Troponin elevations can occur in a variety of conditions beyond ACS, such as myocarditis, pericarditis, heart failure, sepsis, pulmonary embolism, and renal failure. The diagnosis and management of non-ACS troponin elevations require a careful evaluation of the patient's medical history, physical examination, and laboratory tests. Treatment depends on the underlying cause of the troponin elevation and may involve medications, lifestyle changes, or supportive care. Close monitoring of troponin levels and other laboratory values is necessary to evaluate the response to treatment and assess for any complications.


  1. Beck RW, Kupersmith MJ, Cleary PA, et al.. Fellow eye abnormalities in acute unilateral optic neuritis: experience of the Optic Neuritis Treatment Trial. Ophthalmol. 1993;100(5):691-8. strong>
  2. Indexed at, Google Scholar, Cross Ref

  3. Beck RW, Trobe JD, Optic Neuritis Study Group.What we have learned from the Optic Neuritis Treatment Trial Ophthalmol. 1995;102(10):1504-8.
  4. Indexed at, Google Scholar, Cross Ref

  5. Hoorbakht H, Bagherkashi F. Optic neuritis, its differential diagnosis and management Open J Ophthalmol. 2012;6:65.
  6. Indexed at, Google Scholar,

  7. Petzold A, Wattjes MP, Costello F, et al. The investigation of acute optic neuritis: a review and proposed protocol. Nat Rev Neurol. 2014;10(8):447-58.
  8. Indexed at, Google Scholar, Cross Ref

  9. Shams PN, Plant GT. Optic neuritis: a review. Int MS J. 2009;16(3):82-9.
  10. Indexed at, Google Scholar,

Get the App