Journal of Cancer Clinical Research

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (202) 780-3397

Opinion Article - Journal of Cancer Clinical Research (2025) Volume 8, Issue 1

Revealing the Hidden Danger: Insights into Subclinical Myocardial Dysfunction in Contemporary Cardiology

Article type: Perspective

Home Page URL:  https://www.alliedacademies.org/journal-cancer-clinical-research/

Journal short name: J Can Clinical Res

Volume: 8

Issue: 1

PDF No: 176

Citation: Muller J . Revealing the Hidden Danger: Insights into Subclinical Myocardial Dysfunction in Contemporary Cardiology. J Can Clinical Res. 2025; 8(1):176

*Correspondence to: Jacob Muller, Department of Cardiology, Charité – Universitätsmedizin Berlin, Germany. Email: jacob.muller@charite.de

Received: 27-May-2025, Manuscript No. AACCR-25-169783; Editor assigned: 01-Jun-2025, PreQC No. AACCR-25-169783 (PQ); Reviewed: 15- Jun-2025, QC No. AACCR-25-169783; Revised: 22- Jun-2025, Manuscript No. AACCR-25-169783 (R); Published: 29- Jun-2025, DOI:10.35841/AATCC-8.1.176

Visit for more related articles at Journal of Cancer Clinical Research

Revealing the Hidden Danger: Insights into Subclinical Myocardial Dysfunction in Contemporary Cardiology

Jacob Muller*

Department of Cardiology, Charité – Universitätsmedizin Berlin, Germany

Introduction

Hemorrhagic shock, a critical condition resulting from rapid and severe blood loss, remains a primary cause of preventable trauma-related deaths globally [1, 2, 3, 4, 5]. It is characterized by hypovolemia leading to inadequate tissue perfusion, cellular hypoxia, and ultimately multi-organ failure if not addressed swiftly. Despite significant advancements in trauma care and prehospital response systems, the early identification and targeted treatment of hemorrhagic shock continue to pose major clinical challenges [6, 7, 8].

Traditional management focused heavily on fluid resuscitation and blood product administration. However, contemporary approaches emphasize damage control resuscitation (DCR), which integrates permissive hypotension, hemostatic resuscitation, and rapid surgical control of bleeding. The emergence of point-of-care ultrasonography, lactate clearance monitoring, and viscoelastic testing (e.g., thromboelastography) has revolutionized both the diagnosis and the dynamic monitoring of shock progression [8, 9, 10].

This article aims to synthesize current knowledge on hemorrhagic shock, examining its pathophysiology, diagnostic strategies, and evolving trends in clinical management within both civilian and military trauma settings.

Conclusion

Hemorrhagic shock remains a time-sensitive and complex clinical emergency, demanding a structured and evidence-based approach to improve survival outcomes. Innovations in diagnostics and resuscitation strategies, particularly the integration of point-of-care tools and damage control principles, have reshaped trauma protocols and reduced mortality in recent years.

Going forward, continued research into biomarkers of shock, individualized transfusion strategies, and portable hemostatic technologies will be pivotal in refining patient care. Education, simulation training, and system-level preparedness are equally critical in ensuring rapid response and effective intervention during the golden hour of trauma. By aligning multidisciplinary trauma teams and leveraging technological advancements, healthcare systems can markedly enhance the management of hemorrhagic shock in both urban and austere environments.

References

 References

  1. Cothren, C. C., Moore, E. E., Johnson, J. L., Moore, J. B., & Ciesla, D. J. (2007). Morbidity associated with multiple organ failure after severe trauma. Archives of Surgery, 142(5), 447–451.
  2. Søreide, K., Krüger, A. J., Ellingsen, C. L., & Søreide, E. (2011). Trauma care in Norway: A national survey of trauma system resources and organization. Acta Anaesthesiologica Scandinavica, 55(9), 1142–1148.
  3. Shapiro, N. I., Howell, M. D., Bates, D. W., Angus, D. C., Ngo, L., & Talmor, D. (2006). The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection. Annals of Emergency Medicine, 48(5), 583–590.
  4. Joseph, B., Azim, A., Pandit, V., Sadoun, M., Kulvatunyou, N., Tang, A., & Rhee, P. (2014). Improving trauma care through the use of standard operating procedures. World Journal of Surgery, 38(8), 2006–2012.
  5. Vincent, J. L., Moreno, R., Takala, J., Willatts, S., De Mendonça, A., Bruining, H., ... & Thijs, L. G. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Medicine, 22(7), 707–710.
Get the App