Mini Review - Allied Journal of Medical Research (2023) Volume 7, Issue 1
Nutritional metabolism and recent technology in human health.Chrystal Sun*
Department of Health & Science University, Sam Jackson Park Road, Portland, United States
- *Corresponding Author:
- Chrystal Sun
Department of Health & Science University
Sam Jackson Park Road, Portland, United States
Received: 27-Dec-2022, Manuscript No. AAAJMR-23-85973; Editor assigned: 30-Dec-2022, PreQC No. AAAJMR-23-85973(PQ); Reviewed: 13-Jan-2023, QC No AAAJMR-23-85973; Revised: 18-Jan-2023, Manuscript No. AAAJMR-23-85973(R); Published: 25-Jan-2023, DOI:10.35841/aaajmr-7.1.162
Citation: Sun C. Nutritional metabolism and recent technology in human health. Allied J Med Res. 2023;7(1):162
Sustenance progress, which includes a switch from traditional weight-control methods to modern ones that emphasise high-energy density and low supplement variety, is associated with acquired metabolic disorders. The human diet consists of a variety of components, including both supplements and non-supplements that provide the raw materials needed to power different metabolic cycles in each cell of the body. Through a variety of processes, these components and their metabolites can also regulate the quality of articulation and cell function. While some of these components are useful, others have negative effects. Studies have shown that the constant disturbing effect of supplement digestion and energy homeostasis, caused by either a lack of or an abundance of supplements, causes cell stress, which causes metabolic dysregulation and tissue damage.
Nutritional metabolism, Human health, Acquired metabolic disorders.
Recent developments in high-throughput analysis have aided in a better understanding of digestion and revealed the active role that supplements and their metabolites play in regulating quality articulation and cell function. Supplements and their metabolites serve as fuel sources, building blocks for cell structures, and immediate regulators of protein synthesis. They also act as inducers and repressors of quality articulation. Many of them participate in the control of quality articulation by directly balancing the activities of record factors and by controlling the changes in the epigenetic marks of the genome .
Food is made up of a complicated mixture of various ingredients that can be divided into nutrients and non-nutrients. Traditional classifications of nutrients include macronutrients and micronutrients. Animals and plants do not have the same nutritional needs, and they may also create different nutrient metabolites. Only trace levels of micronutrients, such as vitamins and minerals, are necessary for the healthy operation of critical proteins and enzymes. Typically, considerable amounts of the macronutrients carbohydrates, proteins, and fats are required .
Single supplement treatments, such as fortified milk with vitamin D, iron-fortified cereal, and iodized table salt, were effective in correcting the corresponding supplement deficiencies. However, comparable approaches have had ambiguous results when used to treat acquired metabolic problems that prevail in modern societies. For instance, reducing dietary intake of saturated fat or cholesterol and increasing intake of omega-3 polyunsaturated fatty acids don't appear to be effective in reducing the risk of cardiovascular infections. A growing number of research are dissecting dietary examples to identify potential causes for under- and overnourishment in order to understand the significance of the entire eating routine that is consumed as a usual practice .
The mammalian metabolic apparatus also produces other compounds that are important for metabolism. For instance, cholesterol functions as a membrane building block, a signaling molecule, and a precursor for the production of bile acids and steroid hormones. Through intracellular ligand-activated nuclear receptors, bile acids modulate the metabolism of macronutrients and energy, inflammatory reactions, and detoxification in addition to assisting in the absorption of dietary fats and lipid-soluble substances .
Two frequently mentioned dietary examples are the Mediterranean example and the Western design. The Western-style diet is typically characterized by energy-dense food varieties like margarine, high-fat dairy products, refined grains, as well as handled and red meat, leaving less space for different supplements, especially those coming from products of the soil. The Mediterranean diet, however, contains a high extent of leafy foods, vegetables, whole grains, fish, and poultry with an accent on monounsaturated fats and cell reinforcements. According to epidemiological studies, the Mediterranean diet offers protective and preventive effects against cardiovascular infections, whereas the Western diet is unmistakably linked to dyslipidemia, obesity, hypertension, atherosclerosis, and diabetes .
Traditionally, nutrients have been thought of as food that provides the building blocks for cellular development and proliferation as well as the energy to drive cellular metabolism. However, it is also clear that in addition to these functions, nutrients and their metabolites play a significant role in the facilitation, control, and coordination of the enormous number of cellular activities necessary to preserve cellular homeostasis. Contextual factors including sex, age, and appropriate nutrition supply all affect how well cells work. The prevalence of processed foods in Western-style diets may be a significant contributor to the growth of acquired metabolic disorders in developed cultures.
- Gakidou E, Afshin A, Abajobir AA, et al. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 2017;390:1345-422.
- Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. The lancet. 2005;365(9455):217-23.
- Kelly T, Yang W, Chen CS, et al. Global burden of obesity in 2005 and projections to 2030. Int J Obes. 2008;32(9):1431-7.
- Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87(1):4-14.
- Misra A, Khurana L. Obesity and the metabolic syndrome in developing countries. J Clin Endocrinol Metab. 2008;93:9-30.