Hematology and Blood Disorders

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Mini Review - Hematology and Blood Disorders (2023) Volume 6, Issue 3

Late effects and secondary cancers in childhood leukemia survivors

Gisela Roser*

Department of Health Sciences and Medicine

*Corresponding Author:
Gisela Roser
Department Human Development
University of Lucerne
china
E-mail:gisela@roserunilu.ch

Received:30-Aug-2023,Manuscript No. AAHBD- 23-103253; Editor assigned:02- Sept -2023,PreQC No. AAHBD- 23-103253(PQ); Reviewed:16-Sept-2023,QC No.AAHBD- 23-103253; Revised:21-Sept-2023, Manuscript No. AAHBD- 23-103253(R); Published:28-Sept-2023,DOI:10.35841/ aahbd-6.3.152

Citation: Roser G. Late effects and secondary cancers in childhood leukemia survivors. Hematol Blood Disord. 2023;6(3):152

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Abstract

The survival rates of children with leukaemia, a blood and bone marrow malignancy, have considerably increased as a result of medical improvements. However, there is rising concern over the effects on survivors of childhood leukaemia on their long-term health. The late effects and potential for subsequent cancers in people who have successfully battled childhood leukaemia are explored in this abstract. Children with leukaemia frequently experience a variety of late effects, which are medical conditions that appear months or years after the end of cancer treatment. The type of leukaemia, age at diagnosis, treatments used, and personal vulnerability are a few of the variables that can affect these late effects.

Keywords

Childhood leukemia, chronic health conditions, Lifestyle factors, Radiation therapy

Introduction

Cardiovascular consequences, such as cardiomyopathy and heart failure, endocrine disorders, reduced fertility, problems with growth and development, cognition deficiencies, and an increased risk of chronic health illnesses are common late effects in childhood leukaemia survivors. The survival rates of children with leukaemia have dramatically increased thanks to improvements in treatment.[1].

However, there is rising worry about the effects of childhood leukaemia survivorship on their long-term health. This introduction gives a general overview of the long-term effects and the possibility of subsequent cancers in people who have successfully battled childhood leukaemia. For those who have survived childhood leukaemia, long-term follow-up care is essential due to the possibility of late effects and subsequent cancers.[2].

Essential elements of survivorship care include routine medical screenings and assessments, such as cognition testing, endocrine monitoring, cardiac evaluations, and cancer surveillance. These steps are intended to identify any potential issues early on and address them. The risk of late effects and subsequent malignancies can also be reduced by encouraging good lifestyle practices such eating a balanced diet, getting regular exercise, and abstaining from cigarettes and excessive sun exposure. Healthcare professionals must be aware of any potential long-term consequences and subsequent cancer risks in childhood leukaemia survivors and take appropriate action.[3].

Healthcare practitioners can maximize the wellbeing and quality of life for childhood leukaemia survivors while minimizing the burden of late squeal and lowering the risk of secondary cancers by providing thorough long-term follow-up care and applying preventive methods. The therapy of childhood leukaemia, a bone marrow and blood malignancy, has made considerable strides throughout time, increasing survival rates. As more kids beat leukaemia, focus has shifted to the potential problems and long-term health effects that could affect these juvenile leukaemia survivors. The topic of late effects and secondary cancers in people who have recovered from childhood leukaemia is explored in this introduction.[4].

Childhood leukaemia survivors frequently experience late effects, which are medical conditions that appear months or even years after the end of the cancer therapy. Depending on a number of variables, such as the type of leukaemia, age at diagnosis, treatments received, and personal predisposition, the specific late consequences may differ. A wide range of conditions, including cardiovascular complications (such as cardiomyopathy and heart failure), endocrine disorders, impaired fertility, growth and development problems, neurocognitive deficits, and an elevated risk of chronic health conditions are among the most prevalent late effects seen in childhood leukaemia survivors.[5].

Conclusion

Those who have survived childhood leukaemia may experience long-term repercussions and have a higher risk of getting subsequent cancers. In order to provide the best survival care, consideration of long-term health effects has become essential as more children with leukaemia recover successfully. Common late consequences seen in this population include cardiovascular troubles, endocrine disorders, reduced fertility, growth and development problems, cognition deficiencies, and an increased risk of chronic health concerns. For the long-term health and wellbeing of childhood leukaemia survivors, it is crucial to identify and treat late effects as well as the risk of secondary cancers. To monitor and treat potential problems, thorough follow-up treatment and routine medical exams are essential. The risk of late effects and subsequent malignancies can also be reduced by encouraging good behaviors and lifestyle changes, such as adopting a balanced diet, participating in regular physical activity, and refraining from tobacco use and excessive sun exposure.

References

  1. Gatta G, Botta L, Rossi S et al.Childhood cancer survival in Europe 1999–2007: Results of EUROCARE-5—A population-based study.Lancet Oncol. 2014;15(1):35-47.

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  2. Hudson MM, Ness KK, Gurney JG et al.Clinical ascertainment of health outcomes among adults treated for childhood cancer JAMA. 2013; 309(22):2371-81.

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  3. Morley JE, Vellas B, Van Kan GA et al.Frailtyconsensus: A call to action.Am J Med. 2013;14(6):392-7.

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  4. Van Iersel L, Li Z, Srivastava DK et al.Hypothalamic-pituitary disorders in childhood cancer survivors: Prevalence, risk factors and long-term health outcomesJ Clin Endocr. 2019;104(12):6101-15.

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  5. Aaronson NK, Muller M, Cohen PD et al.Translation, validation, and norming of the Dutch language version of the SF-36 Health Survey in community and chronic disease populations.J Clin Epidemiol. 1998;51(11):1055-68.

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