Journal of Biomedical Imaging and Bioengineering

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Mini Review - Journal of Biomedical Imaging and Bioengineering (2022) Volume 6, Issue 9

Determination of magnetic resonance imaging and effect of multi-phase reactions

Steven Edward*

Department of Neurology, University of Osaka, Japan

*Corresponding Author:
Steven Edward
Department of Community Physiotherapy
University of Osaka

Received:23-Aug-2022, Manuscript No.AABIB-22-80756; Editor assigned: 25-Aug-2022, PreQC No.AABIB-22-80756(PQ); Reviewed:08-Sep-2022, QC No.AABIB-22-80756; Revised:13-Sep-2022, Manuscript No.AABIB-22-80756(R); Published:20-Sep-2022, DOI: 10.35841/2249-622X.9.145

Citation: Edward S. Determination of magnetic resonance imaging and effect of multi-phase reactions: J Biomed Imag Bioeng.2022; 6(9):145

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Multiphase flows are very important in today's industrial processes, as many products are produced from gas-liquid reactions.The hydrodynamics of the wake behind the bubbles is important because the product selectivity is determined by the residence time in these mixing zones. Magnetic Resonance Imaging MRI offers a variety of options for investigating multiphase flows. Here, non-invasive MRI flow measurements are performed on a buoyancy-driven.Taylor bubble that is spatially fixed in water regurgitation. An experimental setup that allows the generation of Taylor bubbles in a horizontal bore MRI scanner is presented. Additionally, a suitable MRI sequence is described that allows time-dependent analysis of the current flow field.


Spin echo, Relaxation curve, Spin echo sequence, Cytotoxic oedema.


However, targeted improvement and optimization of these parameters can only be achieved by examining chemical reactions at the local level with respect to concentration fields and mass transfer coefficients. A good knowledge of the underlying flow dynamics is critical for this, as this is superimposed on chemical reactions and has a large impact on local concentrations and residence times. In contrast to complex flow experiments with bubble swarms, free-rising bubbles in large columns simulated bubble swarm effects, the rise of individual bubbles in confined spaces such as small capillaries is not an experiment. It enables laboratory-scale experimental investigations and provides the system with sufficient functionality [1].

Reduced complexity results in defined and reproducible measurement conditions. These so-called Taylor flows are excellent tools for systematic studies when it comes to fluid dynamics, mass transport and chemical reactions within two-phase flows. They are characterized by elongated spherical bubbles, so-called Taylor bubbles that move inside the capillary and a well-defined thin liquid film separates the bubble from the capillary wall. The final volume-independent rise rate of buoyancy-driven Taylor bubbles in vertically aligned capillaries depends on the relationship between gravity and surface tension [2].

This is affected by the capillary diameter and the properties of the chemicals used. By introducing counter flow, hydrodynamic long-term measurements are possible. The flow rate is set equal to the final velocity of the bubble rise and held in place. Increasing the capillary diameter increases the rising velocity and changes the wake structure behind the bubble. These wake structures can be visualized by particle imaging velocimetry, in which fluorescent particles are dispersed in a liquid phase [3].

In steady flow, particles follow the streamlines of the flow and can be tracked by evaluating the tracer particle ensemble from a series of time-accurate images. Additional laser-induced concentration fields around bubbles Fluorescence measurement this can be done by adding a dye whose fluorescence is quenched on contact with gas moving into the liquid phase. Furthermore, a coordinated chemical reaction system can be applied to visualize local mass transfer via colour change reactions. All of these techniques have strengths and weaknesses, but they are all limited to optically accessible systems and rely on tracers or chemicals that contaminate the system under study [4].

MRI Flow Characterization:

The MRI flow characterization experiments were performed using a Bio Spec 70/20 USR Broker Bio spin MRI GmbH, Germany MRI scanner, equipped with a magnetic field gradient insert BGA12S2, max.Excitation and reception of the MR signal was done by a custom-made radio frequency coil fitting around the test section.depicts the loop-gap resonator constructed from copper foil and chip capacitors mounted on an acrylic tube. One variable tuning capacitor was installed to adjust the RF frequency inside the 7-T magnet to the 1H NMR frequency of approximately 300.3 MHz the RF coil was connected to a preamplifier by an inductively coupled single-turn pickup coil, as shown in 3D-printed scissor lift mechanism was utilized to adjust the vertical distance between the two coils. By moving the pickup coil inside the electromagnetic field created by the RF coil, the system impedance can be matched to 50 Ω, ensuring that reflection losses are avoided during RF transmission and signal reception [5].


For the first time, non-invasive MRI flow measurements of pure, low-viscosity gas-liquid Taylor flow have been successfully performed on a horizontal bore NMR system. A custom Taylor flow-through setup and loop-gap resonator that meet the size and material requirements for NMR compatibility are presented. Long-term measurements were made possible by holding a buoyancy-drive Taylor bubble in a vertical glass capillary using counter current flow of ultrapure water. The flow was visualized by MRI using snapshot FLASH pulse sequences and improved in terms of acquisition time and motion blur. This work represents a first step toward fully resolving the flow field of gas-liquid Taylor flow under relevant flow conditions by using non-invasive MRI measurements, leading to a further understanding of the underlying phenomena



  1. Merker DMass Transfer in Reactive Bubbly Flows–A Single?Bubble Study. Che Eng Technol. 2017;40(8):1391-9.
  2. Indexed at, Google Scholar, Cross Ref

  3. Nogueira S.Flow patterns in the wake of a Taylor bubble rising through vertical columns of stagnant and flowing Newtonian liquids: An experimental study. Chem Eng Sci. 2006;61(22):7199-212.
  4. Indexed at, Google Scholar, Cross Ref

  5. Hayashi K. Terminal velocity of a Taylor drop in a vertical pipe. ACS Sustain Chem Engg. 2021; 39(5);235-38
  6. Indexed at, Google Scholar, Cross Ref

  7. Halling PJ.Biocatalysis in multi-phase reaction mixtures containing organic liquids..Bio Tech Adv. 1987;5(1):47-84.
  8. Indexed at, Google Scholar, Cross Ref

  9. Michalik C. Incremental identification of fluid multi?phase reaction systems.AICHE. 2009;55(4):1009-22.
  10. ,Google Scholar, Cross Ref

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