Journal of Biotechnology and Phytochemistry

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Perspective - Journal of Biotechnology and Phytochemistry (2023) Volume 7, Issue 4

Current advances of dendrobium officinale polysaccharides in dermatology

Yang Lin*

Department of Biotechnology

*Corresponding Author:
Yang Lin
Department of Biotechnology
Santa Clara University
California, United States

Received:26-Jul-2023, Manuscript No. AAJBP-23-109262; Editor assigned:28-Jul-2023, PreQC No. AAJBP-23-109262(PQ); Reviewed:11-Aug-2023, QC No. AAJBP-23-109262; Revised:16-Aug-2023, Manuscript No. AAJBP-23-109262(R); Published:23-Aug-2023, DOI:10.35841/ aajbp-7.3.161

Citation: Lin Y. Current advances of Dendrobium officinale polysaccharides in dermatology. J Biotech and Phytochem. 2023;7(4):161

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Dermatology, the branch of medicine focusing on the study and treatment of skin disorders, has witnessed a significant evolution over the years, with researchers continually exploring new avenues to develop innovative therapies. One such area of exploration involves the utilization of natural compounds for dermatological applications. Dendrobium officinale, a traditional Chinese medicinal plant, has gained attention in recent years due to its polysaccharide-rich composition and potential benefits in dermatology. This article delves into the current advances in harnessing Dendrobium officinale polysaccharides for various dermatological applications [1].

Dendrobium officinale, commonly known as the "Shi Hu" in Traditional Chinese Medicine (TCM), has a rich history of use for various health conditions. One of the most intriguing components of Dendrobium officinale is its polysaccharide content. Polysaccharides are complex carbohydrates that exhibit a range of bioactive properties, including antioxidant, anti-inflammatory, immunomodulatory, and wound-healing effects. In recent years, researchers have turned their attention to these polysaccharides and their potential benefits in dermatology. Free radicals and oxidative stress play a significant role in skin aging and the development of various dermatological conditions. Dendrobium officinale polysaccharides have shown promising antioxidant properties, which can help combat the damaging effects of free radicals. By scavenging these harmful molecules, these polysaccharides may contribute to reducing oxidative stress and thereby preventing premature aging of the skin [2].

Anti-inflammatory effects

Inflammation is a common underlying factor in many skin disorders, such as acne, eczema, and psoriasis. Dendrobium officinale polysaccharides possess anti-inflammatory properties that can help modulate the immune response and alleviate inflammation. These effects may offer a potential avenue for managing inflammatory skin conditions and promoting overall skin health [3].

Wound healing and scar reduction

Wound healing is a complex process that involves various cellular and molecular events. Dendrobium officinale polysaccharides have demonstrated the ability to accelerate wound healing by promoting cell proliferation, collagen synthesis, and angiogenesis. Moreover, their potential to minimize scar formation could have significant implications in improving the cosmetic outcomes of various dermatological procedures and injuries. A balanced immune response is crucial for maintaining healthy skin. Dendrobium officinale polysaccharides have been found to possess immunomodulatory properties, which can help regulate immune reactions within the skin. This can be particularly beneficial in conditions where immune dysfunction contributes to the development of dermatological disorders. The exploration of Dendrobium officinale polysaccharides in dermatology is still in its early stages, and further research is required to fully understand their mechanisms of action and clinical applications. While preliminary studies are promising, the translation of these findings into effective dermatological treatments requires rigorous scientific investigation [4].

The utilization of Dendrobium officinale polysaccharides in dermatology represents a promising frontier in natural-based skin care and treatment. With their antioxidant, anti-inflammatory, wound-healing, and immunomodulatory properties, these polysaccharides hold potential for addressing a range of dermatological conditions, from aging-related concerns to inflammatory disorders. However, it's essential to approach this area of research with scientific rigor and caution. Thorough preclinical and clinical investigations are required to fully understand the mechanisms of action, optimize formulations, and establish the safety and efficacy of Dendrobium officinale-derived treatments. As the field of dermatology continues to evolve, incorporating natural compounds like Dendrobium officinale polysaccharides could open new avenues for improving skin health and overall well-being [5].


The current advances in utilizing Dendrobium officinale polysaccharides for dermatological applications hold great potential. From their antioxidant and anti-aging effects to their anti-inflammatory and wound-healing properties, these polysaccharides offer a multifaceted approach to improving skin health. As research progresses, we may witness the integration of Dendrobium officinale-derived formulations into mainstream dermatological practices, providing patients with novel and effective therapeutic options for various skin conditions.


  1. Yano K, Brown LF, Detmar M. Control of hair growth and follicle size by VEGF-mediated angiogenesis.. J Clin Invest. 2001;107(4):409-17.
  2. Indexed at, Google Scholar, Cross Ref

  3. Xing S, Zhang X, Ke H, et al. Physicochemical properties of polysaccharides from Dendrobium officinale by fractional precipitation and their preliminary antioxidant and anti-HepG2 cells activities in vitro. Chem Cent J. 2018;12:1-0.
  4. Indexed at, Google Scholar, Cross Ref

  5. Tang H, Zhao T, Sheng Y, et al. Dendrobium officinale Kimura et Migo: a review on its ethnopharmacology, phytochemistry, pharmacology, and industrialization. Evid Based Complement Alternat Med. 2017;2017.
  6. Indexed at, Google Scholar, Cross Ref

  7. Szymanska R, Pospisil P, Kruk J. Plant-derived antioxidants in disease prevention. Oxid Med Cell Longev. 2016;2016.
  8. Indexed at, Google Scholar, Cross Ref


  9. Schelke LW, Velthuis P, Kadouch J, et al. .Early ultrasound for diagnosis and treatment of vascular adverse events with hyaluronic acid fillers. J Am Acad Dermatol. 2023;88(1):79-85.
  10. Indexed at, Google Scholar, Cross Ref

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