Journal of Pregnancy and Neonatal Medicine

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Editorial - Journal of Pregnancy and Neonatal Medicine (2025) Volume 9, Issue 1

Advances in Neonatal Resuscitation: Best Practices and Guidelines

Likuan Wei *

Department of Obstetrics and Gynecology, University Emergency Hospital, Romania

*Corresponding Author:
Likuan Wei
Department of Obstetrics and Gynecology, University Emergency Hospital, Romania
E-mail: wlikuan@ueh.ro.co.in

Received: 02-Jan-2025, Manuscript No. AAPNM-25-162852; Editor assigned: 03-Jan-2025, PreQC No. AAPNM-25-162852 (PQ) Reviewed:17-Jan-2025, QC No. AAPNM-25-162852Revised:24-Jan-2025, Manuscript No. AAPNM-25-162852 (R); Published:28-Jan-2025, DOI: 10.35841/aapnm-9.1.246

Citation: Wei L. Advances in Neonatal Resuscitation: Best Practices and Guidelines. J Preg Neonatal Med. 2025;9(1):246

Visit for more related articles at Journal of Pregnancy and Neonatal Medicine

Abstract

   

Introduction

Neonatal resuscitation is a critical aspect of newborn care, aimed at restoring adequate respiratory and circulatory function in infants who are unable to breathe or maintain oxygenation immediately after birth. Advances in neonatal resuscitation techniques, equipment, and guidelines have dramatically improved the survival rates and outcomes for neonates, particularly those born prematurely or with other complications. This short communication outlines the best practices and recent advancements in neonatal resuscitation, focusing on updated guidelines and key innovations [1].

Neonatal Resuscitation Guidelines

The Neonatal Resuscitation Program (NRP), developed by the American Heart Association (AHA) and the American Academy of Pediatrics (AAP), provides evidence-based guidelines for neonatal resuscitation. The guidelines have evolved over the years, incorporating new research findings, technological advancements, and improved training strategies for healthcare providers. The most recent NRP guidelines emphasize a few key principles [2].

Resuscitation begins with an immediate assessment of the newborn’s condition, including the need for stimulation, clearing of airways, and monitoring of heart rate and respiratory effort. If the infant is not breathing or has a heart rate less than 100 beats per minute (bpm), resuscitation is required. Gentle stimulation, such as rubbing the back, can help initiate breathing in some infants, especially those born at term or near term. Ensuring a patent airway is crucial in neonatal resuscitation [3]. New recommendations emphasize the use of clear suctioning for airway management, especially for neonates born with meconium in the airways, although suctioning is now limited to when the infant is not actively crying or breathing. The primary goal in neonatal resuscitation is to establish adequate ventilation and oxygenation. For neonates who fail to breathe spontaneously, positive pressure ventilation (PPV) using a bag-valve-mask (BVM) is recommended.

CPR (cardiopulmonary resuscitation) is initiated if the heart rate remains below 60 bpm despite adequate ventilation. The emphasis is on gentle and effective ventilation with sufficient pressure to expand the lungs but avoiding excessive inflation pressures. The use of oxygen during resuscitation has evolved. Recent guidelines suggest starting with room air for term infants unless there are signs of significant hypoxia, in which case supplemental oxygen may be administered. For preterm infants, the administration of low-flow oxygen is generally indicated, with careful monitoring to avoid hyperoxia, which can cause long-term complications like retinopathy of prematurity (ROP) [4]. Chest compressions should be initiated if the heart rate remains below 60 bpm despite adequate ventilation. In cases where chest compressions are required, epinephrine may be administered via the umbilical vein or endotracheal tube if there is no response to initial resuscitative measures.

Recent Advances in Neonatal Resuscitation

Surfactant is a substance that helps reduce surface tension in the lungs, making breathing easier for neonates, especially those born prematurely. Advances in surfactant therapy, including more refined delivery techniques, have contributed significantly to the survival rates of preterm infants. Continuous monitoring technologies, such as pulse oximetry and capnography, have become integral in neonatal resuscitation, providing real-time data on oxygen levels and carbon dioxide exhalation. These tools help guide resuscitation efforts more effectively, ensuring proper ventilation and oxygenation. Advances in simulation training for neonatal resuscitation, including high-fidelity mannequins and virtual reality platforms, have greatly enhanced the ability of healthcare providers to practice and refine resuscitation skills [5,6]. These training programs help ensure preparedness and improve team coordination in real-life emergencies. Research has increasingly supported delayed cord clamping (waiting for 30-60 seconds before clamping the umbilical cord) as a means to improve blood volume and oxygen delivery in the neonate. This practice, when combined with appropriate resuscitation efforts, has shown to improve outcomes in preterm and term infants. Neonatal cooling, or therapeutic hypothermia, is a technique used for neonates with hypoxic-ischemic encephalopathy (HIE) following resuscitation after birth. By lowering the infant’s body temperature, the process helps reduce brain injury and improve neurological outcomes. This approach has significantly improved long-term survival rates and cognitive development in infants with moderate to severe HIE [7-10].

Conclusion

Advances in neonatal resuscitation have led to significant improvements in neonatal survival and long-term health outcomes. Key updates in resuscitation guidelines focus on the importance of early assessment, airway management, effective ventilation, and controlled oxygenation. In addition, technological innovations in monitoring, simulation training, and therapies like surfactant administration and therapeutic hypothermia have further refined resuscitation practices. The continual evolution of neonatal resuscitation techniques, combined with ongoing research and education for healthcare providers, will ensure that even the most vulnerable neonates have the best chance for a healthy start to life. Proper training, adherence to updated guidelines, and the integration of new technologies are essential to optimizing neonatal care and improving outcomes for newborns worldwide.

References

  1. van der Geest BA, de Mol MJ, Barendse IS, de Graaf JP, et al. Assessment, management, and incidence of neonatal jaundice in healthy neonates cared for in primary care: a prospective cohort study. Sci Rep. 2022;12(1):14385.
  2. Indexed at, Google Scholar, Cross Ref

  3. Grajczyk A, D?aman K, Czerwaty K, et al. A Relation between Obstructive Sleep Apnea in Pregnancy and Delivering Small for Gestational Age Infant—A Systematic Review. J Clin Med. 2023;12(18):5972.
  4. Indexed at, Google Scholar, Cross Ref

  5. McHugh A, Breatnach C, Bussmann N, et al. Prenatal prediction of neonatal haemodynamic adaptation after maternal hyperoxygenation. BMC Pregnancy Childbirth. 2020;20(1):1-0.
  6. Indexed at, Google Scholar, Cross Ref

  7. Jahanfar S, Ho JJ, Jaafar SH, et al. Ultrasound for diagnosis of birth weight discordance in twin pregnancies. Cochrane Database Syst Rev. 2021(3).
  8. Indexed at, Google Scholar, Cross Ref

  9. Uta M, Craina M, Marc F, et al. Assessing the Impact of COVID-19 Vaccination on Preterm Birth: A Systematic Review with Meta-Analysis. Vaccines (Basel). 2024;12(1):102.
  10. Indexed at, Google Scholar, Cross Ref

  11. Tousty P, Fraszczyk-Tousty M, Dzidek S, et al. Low-Dose Aspirin after ASPRE—More Questions Than Answers? Current International Approach after PE Screening in the First Trimester. Biomedicines. 2023;11(6):1495.
  12. Indexed at, Google Scholar, Cross Ref

  13. Brandstetter M, Neuner M, Dinges C, et al. Fetal Doppler Monitoring During Maternal Open-Heart Surgery: Case report and key aspects of a multidisciplinary challenge. Eur J Obstet Gynecol Reprod Biol. 2023.
  14. Indexed at, Google Scholar, Cross Ref

  15. Ionescu CA, Calin D, Navolan D, et al. Alobar holoprosencephaly associated with a rare chromosomal abnormality: Case report and literature review. Medicine (Baltimore). 2018;97(29).
  16. Indexed at, Google Scholar, Cross Ref

  17. Dodd JM, Andersen C, Dickinson JE, et al. Fetal middle cerebral artery Doppler to time intrauterine transfusion in red?cell alloimmunization: a randomized trial. Ultrasound Obstet Gynecol.
  18. Indexed at, Google Scholar, Cross Ref

  19. Mead MJ, McWhorter CA, Rodgers MD, et al. Does maternal vitamin D status influence placental weight or vascular and inflammatory pathology? Secondary analysis from the Kellogg Pregnancy Study. J Steroid Biochem Mol Biol. 2023;233:106358.
  20. Indexed at, Google Scholar, Cross Ref

Get the App