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Journal of RNA and Genomics

An open access publication – will publish high-quality, peer-reviewed articles addressing most aspects of short and long coding / non-coding RNA biology and application in biotechnology and therapy. The journal aims toward the worldwide dissemination of conceptual reviews and contemporary research findings related to RNA structure and function and genomics.

ISSN: 1747-0854

Archives

microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection

Authors : Lawrence Carpio, Zachary Klase, William Coley, Irene Guendel, Sarah Choi, Rachel Van Duyne, Aarthi Narayanan, Kylene Kehn-Hall, Laurent Meijer, Fatah Kashanchi*
RNA interference plays a significant role in manipulating cellular and viral mechanisms to maintain latency during HIV-1 infection. HIV-1 produces several microRNAs including one from the TAR element which alter the host’s response to infection
Abstract | Full-Text | PDF

RNAi effects on actin mRNAs in Homalodisca vitripennis cells

Authors : Cristina Rosa, Shizuo G Kamita, Haley Dequine, Ha Wuriyanghan, John A Lindbo, Bryce W Falk*
The xylem feeding leafhopper Homalodisaca vitripennis (H. vitripennis) is an unusually robust and efficient vector of Xylella fastidiosa, a Gram-negative bacterium which causes several very important plant diseases. Here we investigated RNA interfere
Abstract | Full-Text | PDF

Cell-specific RNA interference by peptide-inhibited-peptidaseactivated siRNAs

Authors : Sandra Koehn, Hendrik W Schaefer, Mirko Ludwig, Natja Haag, Ulrich S Schubert, Lydia Seyfarth, Diana Imhof, Udo R Markert, Tobias G Poehlmann*
The use of chemically-synthesized short interfering RNAs (siRNAs) is the key method of choice to manipulate gene expression in mammalian cell cultures and in vivo. Several previous studies have aimed at inducing cell-specific RNA interference (RNAi)
Abstract | Full-Text | PDF
The interleukin (IL)-13 pathway and its associated transcription factor, signal transducer and activator of transcription 6 (STAT6), have been clearly implicated in the pathogenesis of bronchial asthma. We have developed a system to effectively scree
Abstract | Full-Text | PDF
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