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Journal of RNA and Genomics

An open access publication – will publish high-quality, peer-reviewed articles addressing most aspects of short and long coding / non-coding RNA biology and application in biotechnology and therapy. The journal aims toward the worldwide dissemination of conceptual reviews and contemporary research findings related to RNA structure and function and genomics.

ISSN: 1747-0854

Archives

Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region

Authors : Kazuo Suzuki, Toshiaki Shijuuku, Toshihiko Fukamachi, John Zaunders, Gilles Guillemin, David Cooper and Anthony Kelleher
In addition to the degradation of homologous RNAs through the RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) can in some systems induce cytosine methylation and transcriptional silencing of homologous promoters. Targeting of HIV-1 b
Abstract | Full-Text | PDF

PCR-based expression analysis and identification of microRNAs

Authors : David P Lu, Rebecca L Read, David T Humphreys, Fiona M Battah, David I K Martin and John E J Rasko
microRNAs (miRNAs) are small RNAs that regulate translation and hence control a variety of cellular processes in metazoans. The quantitation and identification of miRNAs has been hampered by their small size and low abundance. Here we describe two ro
Abstract | Full-Text | PDF
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