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All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

An open access publication – will publish high-quality, peer-reviewed articles addressing most aspects of short and long coding / non-coding RNA biology and application in biotechnology and therapy. The journal aims toward the worldwide dissemination of conceptual reviews and contemporary research findings related to RNA structure and function and genomics.

ISSN: 2591-7781


In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs

Authors : Florie Borel, Richard van Logtenstein, Annemart Koornneef, Piotr Maczuga, Tita Ritsema, Harald Petry, Sander JH van Deventer, Peter LM Jansen, Pavlina Konstantinova*
ABC transporters export clinically-relevant drugs and their over-expression causes multidrug resistance. In order to knock-down ABC transporters, ABCC1 and ABCC2, 13 shRNAs were developed. Four shRNA candidates were tested in vivo using self-compleme
Abstract | Full-Text | PDF

RNA silencing of lactate dehydrogenase gene in Rhizopus oryzae

Authors : Ali Hashemi Gheinani, Neda Haghayegh Jahromi, Elisabeth Feuk-Lagerstedt*, Mohammad J Taherzadeh
Rhizopus oryzae is a filamentous fungus, belonging to the order Mucorales. It can ferment a wide range of carbohydrates hydrolyzed from lignocellulosic materials and even cellobiose to produce ethanol. However, R. oryzae also produces lactic acid as
Abstract | Full-Text | PDF